Myths and Misconceptions around Antibiotic Resistance: Time to Get Rid of Them

Amábile-Cuevas, Carlos F.

doi:10.3947/ic.2022.0060

Cited by 12 publications

(11 citation statements)

References 73 publications

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“…ASPs are associated with decreases in antibiotic use, duration of administration, and duration of hospitalization [ 45 ]. However, few studies have focused on the relationship between an ASP and clinical outcomes, such as the incidence of antibiotic-resistant bacterial strains and changes in survival rates [ 46 ]. Although our hospital monitors the incidence of antibiotic-resistant bacterial strains, there has been insufficient analysis of its relationship with the ASP.…”

Section: Discussion and Perspectivesmentioning

confidence: 99%

Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea

Lee,

Cho

et al. 2024

Korean J Intern Med

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Antimicrobial stewardship programs (ASPs) can lower antibiotic use, decrease medical expenses, prevent the emergence of resistant bacteria, and enhance treatment for infectious diseases. This study summarizes the stepwise implementation and effects of ASPs in a single university-affiliated tertiary care hospital in Korea; it also presents future directions and challenges in resource-limited settings. At the study hospital, the core elements of the ASP such as leadership commitment, accountability, and operating system were established in 2000, then strengthened by the formation of the Antimicrobial Stewardship (AMS) Team in 2018. The actions of ASPs entail key components including a computerized restrictive antibiotic prescription system, prospective audit, post-prescription review through quantitative and qualitative intervention, and pharmacy-based interventions to optimize antibiotic usage. The AMS Team regularly tracked antibiotic use, the effects of interventions, and the resistance patterns of pathogens in the hospital. The reporting system was enhanced and standardized by participation in the Korea National Antimicrobial Use Analysis System, and educational efforts are ongoing. Stepwise implementation of the ASP and the efforts of the AMS Team have led to a substantial reduction in the overall consumption of antibiotics, particularly regarding injectables, and optimization of antibiotic use. Our experience highlights the importance of leadership, accountability, institution-specific interventions, and the AMS Team.

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Section: Discussion and Perspectivesmentioning

confidence: 99%

Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea

Lee,

Cho

et al. 2024

Korean J Intern Med

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“…The role played by patients in regulating antibiotic use, and therefore AR, is clear with several studies showing that clinicians expected by the patient to prescribe antibiotics are more likely to do so [ 22 , 23 ]. Furthermore, a significant proportion of patients do not complete a full course of antibiotics, a factor historically associated with increased AR [ 21 , 24 – 27 ], although this has been called into question in recent years [ 28 , 29 ]. Campaigns aimed at educating the wider public about contributors to AR have been associated with reduced AR rates, yet evaluation of the effectiveness of such campaigns has often not been conducted [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

Skewed perception of personal behaviour as a contributor to antibiotic resistance and underestimation of the risks

Smith,

Buchan

2023

PLoS ONE

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The increasing prevalence of antibiotic-resistant bacteria poses a significant threat to global human health. Countering this threat requires the public to understand the causes of, and risks posed by, antibiotic resistance (AR) to support changing healthcare and societal approaches to antibiotic use. To gauge public knowledge, we designed a questionnaire to assess awareness of causes of AR (both personal and societal) and knowledge of absolute and relative risks posed by antibiotic-resistant bacteria. Our findings reveal that while >90% respondents recognized personal behaviours as limiting AR, few individuals recognized the importance of societal factors e.g. the use of antibiotics in livestock. Furthermore, more respondents named viruses (either by name or as a group) than bacteria as reasons to take antibiotics, indicating lack of understanding. The absolute numbers of current and predicted future deaths attributed to antibiotic-resistant bacteria were under-estimated and respondents were more concerned about climate change and cancer than AR across all age groups and educational backgrounds. Our data reveal that despite heightened public awareness of infection-control measures following the COVID-19 pandemic, there remains a knowledge gap related to contributors and impacts of increasing numbers of antibiotic-resistant bacteria.

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“…Antibiotic-resistant bacteria are increasing worldwide, making it difficult to select empirical antibiotics [ 14 86 87 ]. Antibiotic resistance threatens the treatment of infectious diseases and increases mortality [ 86 ].…”

Section: Recommendationsmentioning

confidence: 99%

Korean Guidelines for Use of Antibiotics for Intra-abdominal Infections in Adults

et al. 2022

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The guidelines are intended to provide practical information for the correct use of antibiotics for intra-abdominal infections in Korea. With the aim of realizing evidence-based treatment, these guidelines for the use of antibiotics were written to help clinicians find answers to key clinical questions that arise in the course of patient care, using the latest research results based on systematic literature review. The guidelines were prepared in consideration of the data on the causative pathogens of intra-abdominal infections in Korea, the antibiotic susceptibility of the causative pathogens, and the antibiotics available in Korea.

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Myths and Misconceptions around Antibiotic Resistance: Time to Get Rid of Them

Cited by 12 publications

References 73 publications

Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea

Implementing antimicrobial stewardship: lessons and perspectives from a university-affiliated tertiary hospital in Korea

Skewed perception of personal behaviour as a contributor to antibiotic resistance and underestimation of the risks

Korean Guidelines for Use of Antibiotics for Intra-abdominal Infections in Adults

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