Abstract:We focus on exploring the antihepatic fibrosis effect of Myrrhone (Myr), a compound extracted from myrrh, and its effective target. Mouse hepatic stellate cells (HSCs) were cultured in vitro and activated by transforming growth factor‐β induction. After Myr intervention, cell viability was assessed by the Cell Counting Kit‐8 assay. The α‐smooth muscle actin(α‐SMA) and Collagen I levels were measured by immunofluorescence, and the expressions of tumor necrosis factor‐α, interleukin‐6, and matrix metalloproteina… Show more
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