Myron Prinzmetal 1908–1987: The man behind the variant angina

Roguin, Ariel

doi:10.1016/j.ijcard.2006.11.217

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“…Variant angina was first described by Prinzmetal in 1959 [Roguin, 2008;Prinzmetal et al 1959]. He described this type of angina as a disease of spontaneous vasospasm of major coronary arteries due to increased vessel tonus.…”

Section: Discussionmentioning

confidence: 99%

A rare cause of cardiogenic shock: variant angina

Akhundova

Sünbül

Bozbay

et al. 2014

Therapeutic Advances in Cardiovascular Disease

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Variant angina (VA) is a clinical syndrome caused by spontaneous vasospasm of the epicardial coronary artery which is characterized by episodes of angina. Endothelial dysfunction and neurohormonal hyperactivity are important factors in pathogenesis of VA. Although patient prognosis is good, VA may be one of the reasons of sudden cardiac death (SCD) in case of persistent ST segment elevation and malignant arrhythmias. Therefore, early treatment of VA is crucial for prevention of malignant arrhythmias and SCD. In this case report we describe a case of VA presented with cardiogenic shock and malignant ventricular arrhythmia.

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Section: Discussionmentioning

confidence: 99%