Myositis in the course of the systemic form juvenile idiopathic arthritis

Gietka, Piotr; Rutkowska-Sak, Lidia; Lisowska, Barbara

doi:10.5114/reum.2014.42801

Cited by 3 publications

(3 citation statements)

References 13 publications

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“…None of our 44 patients had myositis, a rare feature of JIA [40][41][42], or physis involvement. Destructive lesions were seen in single cases and in the JIA-confirmed group only (Table 3).…”

Section: Discussionmentioning

confidence: 78%

Ankle Magnetic Resonance Imaging in Juvenile Idiopathic Arthritis Versus Non-Juvenile Idiopathic Arthritis Patients with Arthralgia

Ostrowska

Gietka

et al. 2022

JCM

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This retrospective case–control study aimed to evaluate whether Magnetic Resonance Imaging (MRI) enables differentiation of ankle arthritis in Juvenile Idiopathic Afrthritis JIA from ankle arthralgia of unknown aetiology in patients clinically suspected of JIA. Forty-four children, at ages 5–16, who underwent MRI of the ankle from January 2016 to March 2021 for clinically suspected active ankle arthritis in the course of JIA were included. MRI findings in both groups—patients with the final diagnosis of JIA and without final diagnosis of JIA—were compared and scored. The sum of the scores of 22 ankle lesions in an individual patient (active, destructive and developmental), so-called the MRI summarized score, was calculated and tested in terms of the most optimal diagnosis of JIA. Interobserver agreement was calculated. Inflammatory features were seen on MRI in 38 out of all the included patients (86%). The most common lesions in both groups were effusion in the tibio-talar joint (68% in JIA and 64% in the arthralgia group) and effusion in subtalar joint (64% in JIA vs. 59% in the arthralgia group). In general, more lesions were identified in the JIA group than in non-JIA. However, only tenosynovitis was significantly more common in the JIA vs. non-JIA group (p = 0.031). The MRI summarized score did not allow for discrimination between ankle arthritis in JIA from non-JIA patients; the best levels of sensitivity (32%), specificity (91%), positive predictive value PPV (78%) and negative predictive value NPV (57%) were achieved only at the cut-off point of 10.

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Section: Discussionmentioning

confidence: 78%

Ankle Magnetic Resonance Imaging in Juvenile Idiopathic Arthritis Versus Non-Juvenile Idiopathic Arthritis Patients with Arthralgia

Ostrowska

Gietka

et al. 2022

JCM

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“…Myositis and muscle wasting can occur in some patients with JIA [ 35 , 36 , 37 , 38 , 39 , 40 ]. Myositis may be triggered by biological treatment in JIA [ 35 ], and may be an element of JIA, a systemic subtype [ 36 , 37 , 38 ]. US has 82.9% sensitivity for detecting histologically proven myositis [ 11 , 39 ].…”

Section: Update In Ultrasoundmentioning

confidence: 99%

Advances in Musculoskeletal Imaging in Juvenile Idiopathic Arthritis

et al. 2022

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Over the past decade, imaging of inflammatory arthritis in juvenile arthropathies has significantly advanced due to technological improvements in the imaging modalities and elaboration of imaging recommendations and protocols through systematic international collaboration. This review presents the latest developments in ultrasound (US) and magnetic resonance imaging (MRI) of the peripheral and axial joints in juvenile idiopathic arthritis. In the field of US, the ultra-wideband and ultra-high-frequency transducers provide outstanding spatial resolution. The more sensitive Doppler options further improve the assessment and quantification of the vascularization of inflamed tissues, and shear wave elastography enables the diagnosis of tissue stiffness. Concerning MRI, substantial progress has been achieved due to technological improvements in combination with the development of semiquantitative scoring systems for the assessment of inflammation and the introduction of new definitions addressing the pediatric population. New solutions, such as superb microflow imaging, shear wave elastography, volume-interpolated breath-hold examination, and MRI-based synthetic computed tomography open new diagnostic possibilities and, at the same time, pose new challenges in terms of clinical applications and the interpretation of findings.

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“…"Effusion/synovial thickening" was considered altogether as a single item as it is often difficult to differentiate these two findings by MRI without intravenous administration of contrast [22]. In addition to synovitis and osteitis, other inflammatory lesions that may be seen in children with JIA include bursitis, enthesitis and myositis [23][24][25][26]. Inflammation may also involve the triradiate cartilage and growth plates.…”

Section: Introductionmentioning

confidence: 99%

MRI Findings in Hip in Juvenile Idiopathic Arthritis

Ostrowska

Gietka

Mańczak

et al. 2021

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The aim of this study was to evaluate if magnetic resonance imaging allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology in juveniles clinically suspected for hip arthritis. This was a retrospective observational study which included 97 children with clinically suspected hip arthritis. Each hip was assessed and scored in MRI for signs of active and destructive inflammatory lesions and developmental lesions. MRI findings between JIA-confirmed patients and without final diagnosis of JIA were compared and the MRI summarized score was calculated, as the sum of scorings of all 24 hip lesions in an individual patient (i.a., effusion, synovitis, bone marrow edema, enthesitis). MRI showed at least one lesion in the majority of patients (95 patients; 98%). Effusion was the most common feature, followed by bone marrow oedema and synovitis. All lesions were more common in patients with a final diagnosis of JIA, especially synovitis and enthesitis (p = 0.037 and p = 0.047). The MRI summarized score was significantly higher in the JIA group than the non-JIA group: 3 (2–5) vs. 2 (2–2), respectively, p = 0.002. Using a cut-off score of 6, the MRI summarized score showed 25% sensitivity and 100% specificity indicating a good ability in discriminating hip arthritis during JIA from non-JIA patients. MRI allows hip arthritis in JIA to be differentiated from hip arthralgia of unknown etiology with good specificity, thus, may be helpful in confirming the diagnosis of JIA.

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Myositis in the course of the systemic form juvenile idiopathic arthritis

Cited by 3 publications

References 13 publications

Ankle Magnetic Resonance Imaging in Juvenile Idiopathic Arthritis Versus Non-Juvenile Idiopathic Arthritis Patients with Arthralgia

Ankle Magnetic Resonance Imaging in Juvenile Idiopathic Arthritis Versus Non-Juvenile Idiopathic Arthritis Patients with Arthralgia

Advances in Musculoskeletal Imaging in Juvenile Idiopathic Arthritis

MRI Findings in Hip in Juvenile Idiopathic Arthritis

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