“…Organ involvement is often more extensive than was previously thought; neurological expression and pulmonary disease, erosive arthritis, various skin signs, and vasculitis have been added to the clinical picture 3,4,5,6,7,8,9,10,11,12,13,14,15 . Organ involvement is often more extensive than was previously thought; neurological expression and pulmonary disease, erosive arthritis, various skin signs, and vasculitis have been added to the clinical picture 3,4,5,6,7,8,9,10,11,12,13,14,15 .…”