Myositis due toCryptococcus neoformansin a Diabetic Patient

Abstract

We report a rare case of cryptococcal myositis with dissemination to lung in a 66-year-old diabetic woman who had no apparent risk factors for cryptococcal disease. She visited the hospital with a continuous pain in the right thigh and fever despite of treatment with antibiotics. She developed a localized lung infiltration. Crytococcus neoformans was isolated from the abscess of the right thigh and confirmed by molecular identification with DNA sequence analysis.Biopsy of the involved lung showed numerous budding yeasts consistent with Cryptocococcus species. The patient was successfully treated with surgical drainage and systemic antifungal agents.

Two Cases of Cryptococcuria Developed as Isolated Cryptococcuria and Disseminated Cryptococcosis

“…Meningoencephalitis and pulmonary infections are frequently encountered manifestations of cryptococcosis [3], but disseminated infection can involve any other anatomic sites [4] such as skin, eyes, genitourinary tract, gastrointestinal tract and abdominal cavity. There are various kinds of cryptococcal infections reported such as meningoencephalitis [5], pneumonia [6], lymphadenitis [7], colonic infection [8], peritonitis [9], cutaneous lesions [10], osteomyelitis [11], myositis [12] and chorioenteritis [13]. However there has been no cryptococcuria reported yet, we are first reporting two cases of cryptococcuria in Korea.…”