Myopia management with naturalvue (etafilcon a) multifocal 1 day contact lenses: continuing evidence from clinical practice

Aller, Thomas; Achenbach, Peg; Cooper, Jeff; Dillehay, Sally; Jamal, Nadine; Jeruss, Jeff; OʼConnor, Brett; Ostrom, Hal; Watanabe, Ron; Zaunbrecher, Amber

doi:10.1016/j.clae.2019.10.079

Cited by 3 publications

(6 citation statements)

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“…Although before and after treatment comparisons have limitations, they have been used to evaluate other myopia control interventions, as they are the only method of evaluating the efficacy of treatment in individual patients. [35][36][37][38] Comparisons to data in control groups 17,18,25,[39][40][41] and to the average progression of refractive error and axial length in virtual control groups of age and ethnicity matched patients from meta-analyses [30][31][32][33][34] can help gauge the success of…”

Section: Discussionmentioning

confidence: 99%

“…This approach of using an age and/or ethnicity matched virtual control group has been used in other studies to evaluate myopia control. [37][38][39][40][41] The mean refractive error and axial length progression for each child in the age and ethnicity matched virtual control group were calculated based on the data in the meta-analyses. [30][31][32][33][34] Both refractive error progression (P < 0.0001; Figure 2) and axial length elongation (P < 0.0001; Figure 3) were significantly lower throughout 3 years of wear of NVMF lenses compared with a virtual control group of age and ethnicity matched myopic children from published meta-analyses.…”

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confidence: 99%

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Reduction of Myopic Progression Using a Multifocal Soft Contact Lens: A Retrospective Cohort Study

Cooper¹,

OʼConnor²,

Aller³

et al. 2022

OPTH

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To evaluate myopia progression over an approximately 6-year follow-up period in children and young adults wearing a commercially available, daily disposable, soft multifocal contact lens with an extended depth of focus (center distance) design. Methods: This retrospective cohort analysis included data from 196 patients of mean (SD) age 12.3 (2.7) years (range, 5-20 years), fit with the NaturalVue Multifocal (NVMF) contact lens at 15 practices in the United States over 6 years. All patients showed at least −0.50D of myopic progression in at least one eye prior to wearing the lens. Data from the right eye were analyzed. One-way ANOVA with Tukeys post-hoc t-tests were used for statistical analysis, with a significance level set at P < 0.05. Results: After wearing these lenses for 6-72 months, the average myopia progression slowed by approximately 0.84 D or 85% compared to baseline, which was statistically significant at all time points (P < 0.0001). Frequency distribution revealed that 91% of wearers showed a decrease in myopia progression compared to baseline, with 79% of wearers showing a ≥70% reduction in myopia progression. The average change in axial length in a subset of the population over 47 months of follow-up was approximately 0.10 mm/year. Compared with changes expected in an age-and ethnicity-matched myopic virtual control group obtained from published meta-analysis data, both myopic refractive error progression and axial elongation were significantly lower in NVMF wearers at 12, 24 and 36 months (P < 0.001). Analysis of the age-and ethnicity-matched virtual control group predicted that the Cumulative Absolute Reduction of axial Elongation (CARE) value over 3 years would be 0.45 mm. Conclusion: Wearers of the soft multifocal contact lens displayed significant reductions in myopia progression throughout a follow-up period of 6 years.

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Section: Discussionmentioning

confidence: 99%

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confidence: 99%

Reduction of Myopic Progression Using a Multifocal Soft Contact Lens: A Retrospective Cohort Study

Cooper¹,

OʼConnor²,

Aller³

et al. 2022

OPTH

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“…Researchers have previously addressed this issue by using age-and/or ethnicity-matched virtual control groups to provide a reasonable assessment of the efficacy of a myopia control intervention. 14,[25][26][27][28][29] In this analysis, children treated using the treatment algorithm were age-and ethnicity-matched against the values predicted by Brennan's model of predicted cycloplegic spherical equivalent autorefraction and axial length changes in untreated Asian and non-Asian pediatric myopes. [30][31][32] Formulae were derived from Brennan's published work to optimize the accuracy of each treated child's matched values, and each child's age was advanced by 1 year annually to ensure accurate age matching at all time points.…”

Section: Discussionmentioning

confidence: 99%

Retrospective Analysis of a Clinical Algorithm for Managing Childhood Myopia Progression

et al. 2022

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SIGNIFICANCE:As the myopia epidemic unfolds, there is growing urgency to identify and implement effective interventions to slow myopia progression. This investigation evaluated the effectiveness of an evidence-based myopia treatment algorithm in a clinical setting among 342 consecutive children. PURPOSE:This study aimed to evaluate effectiveness of a clinical treatment algorithm for myopia progression in children.METHODS: A retrospective cohort analysis was performed using data from myopic children treated for at least 1 year with a defined treatment algorithm incorporating orthokeratology, multifocal lenses, and atropine. The main outcome measures were the percentage of children experiencing ≤0.25 D of myopic cycloplegic spherical equivalent autorefraction (CSER) progression and ≤0.10 mm of axial elongation at 1, 2, and 3 years. The secondary outcome measures were the cumulative absolute reduction of axial elongation values derived from age-and ethnicitymatched virtual control data at 1, 2, and 3 years.RESULTS: Mean annual CSER change values (excluding orthokeratology) were −0.30, −0.20, and −0.13 D at 1, 2, and 3 years, respectively, with 59, 56, and 60% of patients demonstrating ≤0.25 D of change over the prior year. Mean annual axial elongation values were 0.13, 0.12, and 0.09 mm at 1, 2, and 3 years, respectively, with 52, 46, and 65% of patients demonstrating ≤0.10 mm of change over the prior year. The cumulative absolute reduction of axial elongation values were 0.11, 0.20, and 0.29 mm for 1, 2, and 3 years, respectively. CONCLUSIONS:The treatment algorithm demonstrated effective control of CSER and axial length in a diverse group of progressive myopic children, supporting its use for the clinical management of childhood myopia.

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“…These use either a dual-focus optical design or an extendeddepth-of-focus design. [5][6][7] Peripheral myopic defocus has been shown to reduce the progression of axial elongation and refractive error in mammalian animal models, [8,9] and human clinical trials. [10,11] The primary outcome during MM clinical trials has been myopia control efficacy, with less emphasis on the report of initial lens comfort and patient satisfaction.…”

Section: Introductionmentioning

confidence: 99%

“…[10,11] The primary outcome during MM clinical trials has been myopia control efficacy, with less emphasis on the report of initial lens comfort and patient satisfaction. [5,7] Dropout is a significant problem in contact lens wear, with common reasons given by patients include poor vision at distance and near, handling difficulty, and discomfort [12,13]. Such factors may impede the success of implementing myopia control through contact lens-based interventions.…”

Section: Introductionmentioning

confidence: 99%

Patient experience and physiological response to two commercially available daily disposable myopia control contact lenses

Mojarrad

Cargill

Collard

et al. 2022

Contact Lens and Anterior Eye

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Myopia management with naturalvue (etafilcon a) multifocal 1 day contact lenses: continuing evidence from clinical practice

Cited by 3 publications

References 0 publications

Reduction of Myopic Progression Using a Multifocal Soft Contact Lens: A Retrospective Cohort Study

Reduction of Myopic Progression Using a Multifocal Soft Contact Lens: A Retrospective Cohort Study

Retrospective Analysis of a Clinical Algorithm for Managing Childhood Myopia Progression

Patient experience and physiological response to two commercially available daily disposable myopia control contact lenses

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