Myopia and Axial Length Contribute to Vitreous Liquefaction and Nuclear Cataract

Effect of High Myopia on Delayed Absorption of Subretinal Fluid after Scleral Buckling Surgery

“…Myopia is another age-independent risk factor for accelerated posterior vitreous detachment [26]. In high myopic eyes, posterior sclera dilation, vitreous volume increase, and vitreous degeneration and liquefaction occur earlier [27]. This myopic vitreous liquefaction can be explained by an increase in vitreous volume, which exceeds the production of coagulation components that fill the expansion chamber [5].…”

Effect of High Myopia on Delayed Absorption of Subretinal Fluid after Scleral Buckling Surgery

“…Myopia is another age-independent risk factor for accelerated posterior vitreous detachment [26]. In high myopic eyes, posterior sclera dilation, vitreous volume increase, and vitreous degeneration and liquefaction occur earlier [27]. This myopic vitreous liquefaction can be explained by an increase in vitreous volume, which exceeds the production of coagulation components that fill the expansion chamber [5].…”

Intraocular Temperature at Different Sites in Eye Measured at the Beginning of Vitreous Surgery

“…In eyes with longer axial lengths, the temperature just posterior to the lens and mid-vitreous would most likely be higher. Vitreous liquefactions in myopic eyes [ 14 ] may play some role. The temperature posterior to the lens and mid-vitreous was higher in Group A although it was not significantly higher.…”

DNA hypermethylation-mediated downregulation of antioxidant genes contributes to the early onset of cataracts in highly myopic eyes

“…The lens may also lose transparency in other conditions related to vitreous destruction, such as high myopia [30] , [31] . In highly myopic eyes, with much longer axial lengths and larger eyeballs, vitreous liquefaction occurs much earlier than in normal eyes [32] , generating a high-oxygen environment surrounding the lens, thus resulting in earlier onset and higher severity of cataracts than those of ARC. Therefore, the antioxidant capacity within the lens plays an essential role in preventing the development of cataracts.…”

Effect of High Myopia on Delayed Absorption of Subretinal Fluid after Scleral Buckling Surgery

“…Myopia is another age-independent risk factor for accelerated posterior vitreous detachment [26]. In high myopic eyes, posterior sclera dilation, vitreous volume increase, and vitreous degeneration and liquefaction occur earlier [27]. This myopic vitreous liquefaction can be explained by an increase in vitreous volume, which exceeds the production of coagulation components that fill the expansion chamber [5].…”

Intraocular Temperature at Different Sites in Eye Measured at the Beginning of Vitreous Surgery

“…In eyes with longer axial lengths, the temperature just posterior to the lens and mid-vitreous would most likely be higher. Vitreous liquefactions in myopic eyes [ 14 ] may play some role. The temperature posterior to the lens and mid-vitreous was higher in Group A although it was not significantly higher.…”

DNA hypermethylation-mediated downregulation of antioxidant genes contributes to the early onset of cataracts in highly myopic eyes

“…The lens may also lose transparency in other conditions related to vitreous destruction, such as high myopia [30] , [31] . In highly myopic eyes, with much longer axial lengths and larger eyeballs, vitreous liquefaction occurs much earlier than in normal eyes [32] , generating a high-oxygen environment surrounding the lens, thus resulting in earlier onset and higher severity of cataracts than those of ARC. Therefore, the antioxidant capacity within the lens plays an essential role in preventing the development of cataracts.…”

Effect of High Myopia on Delayed Absorption of Subretinal Fluid after Scleral Buckling Surgery

“…Myopia is another age-independent risk factor for accelerated posterior vitreous detachment [26]. In high myopic eyes, posterior sclera dilation, vitreous volume increase, and vitreous degeneration and liquefaction occur earlier [27]. This myopic vitreous liquefaction can be explained by an increase in vitreous volume, which exceeds the production of coagulation components that fill the expansion chamber [5].…”

Intraocular Temperature at Different Sites in Eye Measured at the Beginning of Vitreous Surgery

“…In eyes with longer axial lengths, the temperature just posterior to the lens and mid-vitreous would most likely be higher. Vitreous liquefactions in myopic eyes [ 14 ] may play some role. The temperature posterior to the lens and mid-vitreous was higher in Group A although it was not significantly higher.…”

DNA hypermethylation-mediated downregulation of antioxidant genes contributes to the early onset of cataracts in highly myopic eyes

“…The lens may also lose transparency in other conditions related to vitreous destruction, such as high myopia [30] , [31] . In highly myopic eyes, with much longer axial lengths and larger eyeballs, vitreous liquefaction occurs much earlier than in normal eyes [32] , generating a high-oxygen environment surrounding the lens, thus resulting in earlier onset and higher severity of cataracts than those of ARC. Therefore, the antioxidant capacity within the lens plays an essential role in preventing the development of cataracts.…”