Myopericarditis Revealing Giant Cell Arteritis in the Elderly

Daumas, Aurélie; Rossi, P.; Jacquier, Alexis; Granel, B.

doi:10.3899/jrheum.110934

Cited by 12 publications

(3 citation statements)

References 8 publications

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“…Our study showed a significant interaction between GCA, pericarditis, and younger age (age < 70 years). These findings correspond well with most case reports and case series previously published on the subject . However, several articles have reported cases of adults age > 70 years with simultaneous presentations of both GCA and pericarditis, which usually regressed after corticosteroid treatment .…”

Section: Discussionsupporting

confidence: 91%

“…These findings correspond well with most case reports and case series previously published on the subject. 8,9,19,[28][29][30][31] However, several articles have reported cases of adults age > 70 years with simultaneous presentations of both GCA and pericarditis, which usually regressed after corticosteroid treatment. 12,32-36 A Spanish case report described a 76-year-old female patient with pectoral girdle pain and a pleural effusion on x-ray who was eventually diagnosed with polymyalgia rheumatica (PMR) accompanied by pleuropericarditis and whose high levels of CA-125 indicated serosal involvement, rather than malignancy.…”

Section: Discussionmentioning

confidence: 99%

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Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

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Background Giant cell arteritis (GCA) is an inflammatory disease of unknown etiology affecting adults age > 50 years. GCA (also known as temporal arteritis) is a vasculitis of large and medium‐size vessels that involves the extracranial branches of the carotid artery. Common manifestations include constitutional symptoms, headache, jaw claudication, scalp tenderness, and vision loss. Cardiac involvement in GCA is considered to be as low as 5%, and < 30 cases of pericarditis among GCA patients have been reported in the literature. The aim of this study was to evaluate the association between GCA and pericarditis by conducting a cross‐sectional study utilizing the database of the largest healthcare provider in Israel. Hypothesis GCA is associated with pericarditis. Methods The proportion of past documentation of pericarditis among patients diagnosed with GCA was compared with that of their age‐ and sex‐matched controls. Univariate analysis was performed using the χ2 and t tests; multivariate analysis was performed using logistic regression. Results The study included 4329 GCA patients and 21 611 controls. GCA patients had higher rates of cardiovascular risk factors. Pericarditis was observed in 53 GCA patients and 72 controls (1.22% vs 0.33%, respectively; P < 0.001), significantly higher among GCA patients in comparison with controls. A significant interaction was found between GCA, pericarditis, and young age (<70 years). Conclusions The study showed an independent association between GCA and pericarditis, especially among young patients. Proper screening should be applied whenever a suspicion arises as to the existence of comorbidity in patients with either disease.

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Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Pericarditis among giant cell arteritis patients: From myth to reality

Tiosano

Adler

Azrielant

et al. 2018

Clinical Cardiology

View full text Add to dashboard Cite

show abstract

“…Cardiovascular disease remains a major cause of death in TA [1,14], while in contrast cardiovascular mortality may not be significantly increased in GCA [15,16]. Acute myocarditis is exceedingly rare in GCA, with only a handful of case studies reported [8,17,18]. In TA, cardiac mortality is commonly associated with heart failure, which has been attributed to the hemodynamic effects of ischaemic coronary artery disease, aortic regurgitation or systemic hypertension [3][4][5].…”

Section: Discussionmentioning

confidence: 99%