Myoglobinuria Following Anaesthesia Including Suxamethonium

Hypertrophy of the branchial muscles. A case with unusual features.

“…However, anaesthetic agents, particularly suxamethonium, may provoke a variety of reactions in normal and diseased muscle. Muscle pains (Wylie and Churchill Davidson, 1972), hyperkalaemia (Cooperman, 1970), rhabdomyolysis (Jensen et al, 1968) and contracture in myotonic disorders (Thiel, 1967) have been reported. Careful evaluation ofindividual cases is therefore mandatory; the pathophysiology of the episodes described in our patient remains uncharacterized.…”

Rhabdomyolysis Induced by Anaesthesia With Intraoperative Cardiac Arrest

“…In adult patients the appearance of myoglobin in serum is rare, whereas in a group of children aged 0-10 yr, myoglobin (5-15 (xg/ml serum) could be detected in 40% of the patients after a single i.v. dose of suxamethonium 1 mg/kg (Airaksinen and Tammisto, 1965;Jensen et al, 1968;Ryan, Kagen and Hyman, 1971). Furthermore, congenital factors predisposing to the development of rhabdomyolysis are found in certain types of patients with strabismus more often than in other children (Tammisto et al, 1970).…”

Anesthesia‐induced rhabdomyolysis or malignant hyperthermia: is defining the crisis important?

“…Rhabdomyolysis following exposure to suxamethonium and/or halogenated volatile anesthetic agents has been described in case reports since the 1960s . In 1978, the term “anesthesia‐induced rhabdomyolysis” (AIR) was first used to describe a case of a dystrophic patient who developed rhabdomyolysis following suxamethonium and halothane exposure .…”