Myofascial flap without skin for intra-oral reconstruction 1: animal studies

Abstract

Grafted myofascia in the oral cavity may play a space-making role, and induce regeneration of the mucosal epithelium, associated with the production of keratinocyte growth factor.

Assessment of silk fibroin for the repair of buccal mucosa in a rat model

“…Local tissue, such as mucosa and/or muscle, is suitable for limited tissue defects, but cutaneous or myocutaneous flaps have generally been used for the reconstruction of large soft-tissue defects. Skin flaps are less flexible than the mucosa of the oral cavity, and there is also the problem of continued hair growth in male patients 33 . There are problems with the cosmetic appearance of scar formation and/or deformity of the donor site, and secondary operations are sometimes necessary for loss of skin at the donor site.…”