Myoépithéliome bénin du poumon

Mezni, Faouzi El; Zeddini, A.; Hamzaoui, A.; Ismail, Olfa; Ghrairi, H.; Miled, K. Ben; Smati, B.; Kilani, T.

doi:10.1016/s0761-8417(04)72114-8

Cited by 10 publications

(6 citation statements)

References 7 publications

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“…Since Strickler et al [ 17 ] presented the first case of myoepithelioma in the lung, only a few studies have been reported these neoplasms in the respiratory tract [ 16 , 18 , 19 ], with the lung, bronchus, and trachea as reported locations of the tumors in the pulmonary organs. To the best of our knowledge, excluding our case, only four cases of endotracheal myoepithelioma were reported in the literature [ 7 – 10 ].…”

Section: Discussionmentioning

confidence: 99%

Tracheal myoepithelioma resected by using rigid bronchoscopy: a case report and review of the literature

Mardani

Ebrahimi

Shahriarirad

et al. 2022

J Cardiothorac Surg

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Background Endotracheal tumors are rare in the respiratory system. Myoepitheliomas are benign tumors, which are rarely reported in the respiratory system. Herein, we report a rare case of endotracheal myoepithelioma, which was resected by rigid bronchoscopy. Case presentation A 36-year-old man, presenting with chest pain, dyspnea, stridor, and hemoptysis, was referred to our center with radiological features of near-total tracheal obstruction due to mass. Fiberoptic bronchoscopy with argon plasma coagulation and rigid bronchoscopy with grasper forceps was utilized to resect the mass. Pathological evaluation of the mass demonstrated myoepithelioma. The patient was discharged in good condition. Now, after 6 months, the patient is symptom-free with no evidence of tumor recurrence or re-growth. Conclusions Despite being extremely rare, myoepithelioma should be considered a possible differential diagnosis for endotracheal tumors. Fiberoptic and rigid bronchoscopy management is an effective method for the resection of endotracheal tumors.

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Section: Discussionmentioning

confidence: 99%

Tracheal myoepithelioma resected by using rigid bronchoscopy: a case report and review of the literature

Mardani

Ebrahimi

Shahriarirad

et al. 2022

J Cardiothorac Surg

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“…34 Myoepithelial tumours consist of myoepithelial cells with a solid, nested, reticular, or trabecular architecture in a background of hyaline, myxoid, or chondromyxoid matrix. 35,36,129,[133][134][135] Clear-cell, plasmacytoid, or spindled morphology can be present. Tubule or duct formation should be absent.…”

Section: Myoepithelioma and Myoepithelial Carcinomamentioning

confidence: 99%

“…Typically, myoepithelioma has ≤1 mitosis/10 high-power fields (hpf), whereas myoepithelial carcinoma has 5-32 mitoses/ 10hpf. 35,36,129,[133][134][135][136] One case of pulmonary myoepithelial carcinoma with metastatic disease had only 2-3 mitoses/10hpf. 137 Notably, the malignant criteria used for pulmonary myoepithelial tumours are extrapolated from salivary and soft-tissue myoepithelial tumours, with malignancy of the former based on capsular invasion and infiltrative growth, and malignancy of the latter based on cytologic atypia.…”

Section: Myoepithelioma and Myoepithelial Carcinomamentioning

confidence: 99%

“…Approximately half of myoepithelial tumours primary to the lung occur in association with proximal airways 34 . Myoepithelial tumours consist of myoepithelial cells with a solid, nested, reticular, or trabecular architecture in a background of hyaline, myxoid, or chondromyxoid matrix 35,36,129,133–135 . Clear‐cell, plasmacytoid, or spindled morphology can be present.…”

Section: Myoepithelioma and Myoepithelial Carcinomamentioning

confidence: 99%

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Recent developments in the pathology of primary pulmonary salivary gland‐type tumours

Naso,

Roden

2023

Histopathology

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Primary pulmonary salivary gland‐type tumours are rare neoplasms that are thought to arise from seromucinous glands that are located in the submucosa of large airways. These neoplasms have clinical and pathologic features that are distinct from other pulmonary neoplasms. The majority of primary pulmonary salivary gland‐type tumours are malignant, with the most common entities being mucoepidermoid carcinoma, adenoid cystic carcinoma, and epithelial‐myoepithelial carcinoma. Less commonly seen are myoepithelial carcinoma, hyalinizing clear cell carcinoma, acinic cell carcinoma, secretory carcinoma, salivary duct carcinoma, intraductal carcinoma, and polymorphous adenocarcinoma. Benign salivary gland‐type tumours of the lung include pleomorphic adenoma and sialadenoma papilliferum. Morphologic, immunophenotypic, and molecular features of these neoplasms are largely similar to salivary gland tumours elsewhere, and therefore the exclusion of metastatic disease requires clinical and radiologic correlation. However, the differential diagnostic considerations are different in the lung. The distinction of salivary gland‐type tumours from their histologic mimics is important for both prognostication and treatment decisions. Overall, salivary gland type‐tumours tend to have a more favourable outcome than other pulmonary carcinomas, although high‐grade variants exist for many of these tumour types. Recent advances in our understanding of the spectrum of salivary gland‐type tumours reported in the lung and their diversity of molecular and immunohistochemical features have helped to refine the classification of these tumours and have highlighted a few differences between salivary gland‐type tumours of the lung and those primary to other sites.

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“…Benign myoepithelioma is extremely rare in the lung, to the best of our knowledge; only five cases have been reported in the literature [2-5]. …”

Section: Introductionmentioning

confidence: 99%

Benign myoepithelioma of the lung - a case report and review of the literature

et al. 2010

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IntroductionBenign myoepithelioma is extremely rare in the lung, to the best of our knowledge; only five cases have been reported in the literature.Case ReportAn 18-years woman complained from tiredness and fever during four months. Laboratory findings and fibroscopies were normal. CT of the thorax demonstrated a nodule in the left segment of the Fowler. Left inferior lobectomy was performed comporting a firm nodule of 25 mm, lifting the bronchial mucous membrane. Histologically, there was a proliferation of small cells of a plasmocytoid-type, with a predominantly whorled pattern. No mitotic activity or necrosis was seen in the tumor. Immuhistochemically, the tumor cells positive for smooth muscle actin, vimentine, and S100 protein. They were negatives for cytokeratine, chromogranine and HMB45. The diagnosis of benign myoepithelioma of the lung is so confirmed. The patient recovered well at 6 months follow-up.ConclusionBenign myoepithelioma is a rare pulmonary neoplasm distinct from pleomorphic adenoma, which should be considered in the differential diagnosis of lung nodules.

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Myoépithéliome bénin du poumon

Cited by 10 publications

References 7 publications

Tracheal myoepithelioma resected by using rigid bronchoscopy: a case report and review of the literature

Tracheal myoepithelioma resected by using rigid bronchoscopy: a case report and review of the literature

Recent developments in the pathology of primary pulmonary salivary gland‐type tumours

Benign myoepithelioma of the lung - a case report and review of the literature

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