Myoedema

Hornung, K; Nix, Wilfred A.

doi:10.1159/000116809

Cited by 16 publications

(1 citation statement)

References 13 publications

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“…It is supposedly elicited in different neurological conditions and is considered a normal physiological phenomenon by some neurologists. [1] It has also been elicited in conditions of malnutrition,[2] vitamin deficiencies[3] and anorexia nervosa. [4]…”

Section: Introductionmentioning

confidence: 99%

Reassessment of elicitation of myoedema in evaluation of overt hypothyroidism: A pilot study

Balachandran

Vignesh

Mahesh

et al. 2012

Indian J Endocr Metab

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Section: Introductionmentioning

confidence: 99%

Reassessment of elicitation of myoedema in evaluation of overt hypothyroidism: A pilot study

Balachandran

Vignesh

Mahesh

et al. 2012

Indian J Endocr Metab

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Myoedema in anorexia nervosa: A useful clinical Sign

Morgan¹,

Morgan²

2008

Euro Eating Disorders Rev

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When significant weight loss occurs in anorexia nervosa, routine physical examination may reveal the striking phenomenon of myoedema or muscle mounding. This refers to the way in which a localised short-lasting swelling may be induced in a voluntary muscle as a result of tactile percussion, ideally with a patellar hammer. The present case report describes this finding in a patient with anorexia nervosa and discusses its physiological and clinical significance. It is suggested that as a clinical sign myoedema may be of value in the management of anorexia nervosa by challenging the denial of illness which is so characteristic of it.

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Rippling muscle disease may be caused by “silent” action potentials in the tubular system of skeletal muscle fibers

Lamb

2005

Muscle and Nerve

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Rippling muscle disease (RMD) is a generally benign, myotonic-like myopathy associated with rapid rolling contractions and percussion-induced contractions. These contractions are electrically silent in electromyographic recordings, which is taken as evidence that action potentials are not involved in the phenomena. The pathophysiological mechanisms underlying the symptoms have not been elucidated. Many cases of RMD are caused by mutations in caveolin-3, and aberrations in the tubular system are commonly observed. Here, recent data are discussed showing that action potentials can travel over substantial distances entirely within the transverse and longitudinal tubular systems of a muscle fiber and that stretch can induce such action potentials. Action potentials travelling in the tubular system in most circumstances probably cannot excite the sarcolemma and hence would not be detected. It is suggested that the distinctive contractions in RMD may be due to stretch-induced generation of action potentials within the tubular system.

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Myoedema

Cited by 16 publications

References 13 publications

Reassessment of elicitation of myoedema in evaluation of overt hypothyroidism: A pilot study

Reassessment of elicitation of myoedema in evaluation of overt hypothyroidism: A pilot study

Myoedema in anorexia nervosa: A useful clinical Sign

Rippling muscle disease may be caused by “silent” action potentials in the tubular system of skeletal muscle fibers

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