Myoclonus From Intoxication by Bismuth Iodoform Paraffin Paste (BIPP) Nasopharyngeal Packing

Tan, R H K; Neo, Shermyn; Gan, Yijin Jereme; Fu, Ernest Wei Zhong; Lim, Ming Yann; Li, Hao

doi:10.7759/cureus.18530

Cited by 5 publications

(3 citation statements)

References 18 publications

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“…O'Connor AF reported iodoform toxicity when BIPP was used in packing large defects caused by maxillectomy [ 17 ]. Wilson stated that BIPP, which is used to fill cavities in the mandible, can cause personality changes and insomnia due to encephalopathy after more than seven weeks of use [ 18 ]. The sensitivity to bismuth sulphate or iodoform in bismuth iodoform paraffin paste (BIPP) is type IV delayed hypersensitivity reaction, largely involving T cells and macrophages.…”

Section: Discussionmentioning

confidence: 99%

Role of Dental Professionals in the Management of a Dentigerous Cyst in a Patient With Amelogenesis Imperfecta

Chinnakutti¹,

Mohan²,

Murugesan³

et al. 2022

Cureus

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Amelogenesis imperfecta (AI) is a hereditary condition that affects the clinical features and structure of the enamel. The enamel formation diseases are inherited and might be X-linked, autosomal dominant, recessive, sex-related, or sporadic. Dental professionals should evaluate such patients completely, both clinically and radiographically, to detect any cysts associated with impacted or unerupted teeth. This report describes the case of a 10-year-old patient affected by amelogenesis imperfecta with a dentigerous cyst involving an impacted tooth and an unerupted tooth of the maxilla.

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Section: Discussionmentioning

confidence: 99%

Role of Dental Professionals in the Management of a Dentigerous Cyst in a Patient With Amelogenesis Imperfecta

Chinnakutti¹,

Mohan²,

Murugesan³

et al. 2022

Cureus

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“…In this case, the toxicity was associated with several factors, such as the high extension of the wound, the amount of BIPP packing, and the impaired renal function. After the removal of the BIPP packs, the patient gradually improved over the next two weeks without further intervention (Table 2, Entry 8) [121].…”

Section: Toxicity After Local Application Of Bismuth Iodoform Paraffi...mentioning

confidence: 99%

Bioactive Bismuth Compounds: Is Their Toxicity a Barrier to Therapeutic Use?

Gonçalves,

Matias,

Salvador

et al. 2024

IJMS

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Bismuth compounds are considered relatively non-toxic, with their low solubility in aqueous solutions (e.g., biological fluids) being the major contributing factor to this property. Bismuth derivatives are widely used for the treatment of peptic ulcers, functional dyspepsia, and chronic gastritis. Moreover, the properties of bismuth compounds have also been extensively explored in two main fields of action: antimicrobial and anticancer. Despite the clinical interest of bismuth-based drugs, several side effects have also been reported. In fact, excessive acute ingestion of bismuth, or abuse for an extended period of time, can lead to toxicity. However, evidence has demonstrated that the discontinuation of these compounds usually reverses their toxic effects. Notwithstanding, the continuously growing use of bismuth products suggests that it is indeed part of our environment and our daily lives, which urges a more in-depth review and investigation into its possible undesired activities. Therefore, this review aims to update the pharmaco-toxicological properties of bismuth compounds. A special focus will be given to in vitro, in vivo, and clinical studies exploring their toxicity.

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“…However, neuropsychiatric symptoms can develop from the use of bismuth iodoform paraffin paste gauze. In order to prevent it, clinicians should take into account the patient’s renal and hepatic function as well as the size and condition of the wound [ 362 ].…”

Section: Bismuthmentioning

confidence: 99%

Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table

Machado

Dinis-Oliveira

2023

JCM

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Several heavy metals and other chemical elements are natural components of the Earth’s crust and their properties and toxicity have been recognized for thousands of years. Moreover, their use in industries presents a major source of environmental and occupational pollution. Therefore, this ubiquity in daily life may result in several potential exposures coming from natural sources (e.g., through food and water contamination), industrial processes, and commercial products, among others. The toxicity of most chemical elements of the periodic table accrues from their highly reactive nature, resulting in the formation of complexes with intracellular compounds that impair cellular pathways, leading to dysfunction, necrosis, and apoptosis. Nervous, gastrointestinal, hematopoietic, renal, and dermatological systems are the main targets. This manuscript aims to collect the clinical and forensic signs related to poisoning from heavy metals, such as thallium, lead, copper, mercury, iron, cadmium, and bismuth, as well as other chemical elements such as arsenic, selenium, and fluorine. Furthermore, their main sources of occupational and environmental exposure are highlighted in this review. The importance of rapid recognition is related to the fact that, through a high degree of suspicion, the clinician could rapidly initiate treatment even before the toxicological results are available, which can make a huge difference in these patients’ outcomes.

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Myoclonus From Intoxication by Bismuth Iodoform Paraffin Paste (BIPP) Nasopharyngeal Packing

Cited by 5 publications

References 18 publications

Role of Dental Professionals in the Management of a Dentigerous Cyst in a Patient With Amelogenesis Imperfecta

Role of Dental Professionals in the Management of a Dentigerous Cyst in a Patient With Amelogenesis Imperfecta

Bioactive Bismuth Compounds: Is Their Toxicity a Barrier to Therapeutic Use?

Clinical and Forensic Signs Resulting from Exposure to Heavy Metals and Other Chemical Elements of the Periodic Table

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