Myocarditis with very high troponins: risk stratification by cardiac magnetic resonance

Janardhanan, Rajesh

doi:10.21037/jtd.2016.10.60

Cited by 20 publications

(16 citation statements)

References 25 publications

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“…The cTnI release results from increased permeability of the cardiomyocyte cell membrane and does not exclusively reflect cell necrosis. 12 These findings support myocardial stunning or edema rather than myocarditis in MIS-C. We proved the moderate negative correlation between CRP and EF, which suggests that LV systolic function is conditioned by the degree of inflammation. In KD, myocardial edema is the main finding without or with limited cardiomyocytes necrosis as evidenced by the mild to moderate elevation of cTnI.…”

Section: Discussionsupporting

confidence: 76%

Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage

Vukomanović

Krasić

Prijić

et al. 2021

Pediatric Infectious Disease Journal

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Section: Discussionsupporting

confidence: 76%

Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage

Vukomanović

Krasić

Prijić

et al. 2021

Pediatric Infectious Disease Journal

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“…What makes the presented case different from the newborns reported in other studies was the manifestations of congenital myocarditis, which, according to the reports of SARS-COV-2 cases with myocarditis, predispose them to fetal involvement during pregnancy. However, a negative troponin does not exclude the diagnosis of myocarditis (23,24). In our case, progressive manifestations in the echocardiogram included elevated pulmonary pressure and decreased EF despite relieving respiratory distress and extubation, and response to IVIG and Millerine was in favor of myocarditis.…”

Section: Discussionmentioning

confidence: 58%

Neonatal SARS-CoV-2 Infection and Congenital Myocarditis: A Case Report and Literature Review

Amiraskari

Sayarifard

Kharrazi

et al. 2020

Arch Pediatr Infect Dis

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Introduction: With the outbreak of coronavirus 2019 (SARS-COV-2), the prevention and control of SARS-COV-2 infection in pregnant women and the potential risk of vertical transmission has become a major concern. Case Presentation: We report the case of a newborn in Iran with the manifestations of myocarditis at birth. The diagnosis of SARS-COV-2 infection was confirmed for the mother and the neonate by real-time reverse transcription polymerase chain reaction (rRT-PCR) using a pharyngeal specimen. Conclusions: Based on our literature review, there is still insufficient evidence to determine the effect of SARS-COV-2 infection on the fetus. Given the possibility of cardiac injury in SARS-COV-2 disease and manifestation of congenital myocarditis in our case, maternal vertical transmission of SARS-COV-2 could be considered.

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“…The actual incidence of myocarditis is difficult to estimate as a tissue diagnosis with an endomyocardial biopsy is rarely obtained which id the gold standard for diagnosis in COVID-19 scenario. 16 It is possible that COVID-19 may have caused subclinical myocarditis leading to the aggravation of conduction abnormalities in this patient because she did not have any other overt evidence of myocardial involvement, with normal cardiac biomarkers. Moreover, ACE2 receptors are abundant in the heart and are present in multiple cell types, including macrophages, endothelial cells, smooth muscle cells, and cardiomyocytes.…”

Section: Discussionmentioning

confidence: 86%

A cardiac manifestation in patients with COVID-19: a case series

Ravindranath¹,

Ramaiah²,

Kadloor

2020

Int J Adv Med

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Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus or the coronavirus 2019 (COVID-19) infection is a novel viral infection causing the 2020 pandemic affecting primarily the respiratory system in the form of influenza like illness, severe acute respiratory illness or asymptomatic respiratory illness and other systems. The cardiovascular system may also be affected, with or without a prior history of cardiovascular diseases. Myocardial injury is common among patients hospitalized with COVID-19 due to stress cardiomyopathy, hypoxic injury, ischemic injury due to cardiac microvascular damage or epicardial coronary artery disease and cytokine storm, however rhythm abnormalities is affected rarely in a transient or severe manner causing rhythm disturbances. The concerns about COVID‐19 may result in a delay in proper approach and prompt management in many emergent medical conditions, such as cardiovascular problems. Here, we describe our experience with 4 COVID-19 patients with varied cardiac manifestations presenting to our hospital during the months of September- October 2020.

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Myocarditis with very high troponins: risk stratification by cardiac magnetic resonance

Cited by 20 publications

References 25 publications

Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage

Recent Experience: Corticosteroids as a First-line Therapy in Children With Multisystem Inflammatory Syndrome and COVID-19-related Myocardial Damage

Neonatal SARS-CoV-2 Infection and Congenital Myocarditis: A Case Report and Literature Review

A cardiac manifestation in patients with COVID-19: a case series

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