Myocarditis in Adult-Onset Still’s Disease: Case-Based Review

Gracia‐Ramos, Abraham Edgar; Contreras-Ortíz, Joshua Antonio

doi:10.1007/s10067-019-04814-9

Cited by 16 publications

(36 citation statements)

References 63 publications

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“…The same findings were observed in our case since flagelate dermatoses was associated with probable myocarditis. Cardiac involvement in adult-onset Still's disease (AOSD) usually manifests as a pericardial disease (up to 37% of cases) while myocarditis is uncommon with a prevalence of 7% [9].…”

Section: Discussionmentioning

confidence: 99%

Flagellate dermatoses associated with myocarditis in Adult-onset Still's disease

Toujani

Belhassen

Ouni

et al. 2022

Preprint

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Section: Discussionmentioning

confidence: 99%

Flagellate dermatoses associated with myocarditis in Adult-onset Still's disease

Toujani

Belhassen

Ouni

et al. 2022

Preprint

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“…The pericardium is the most frequently involved (3% to 37% of patients) ( 4 ). Pericarditis is associated with pleural effusion in 60% to 80% of patients ( 5 ). Corticosteroid therapy appears effective, with nonsteroidal anti-inflammatory drugs as the first-line therapy.…”

Section: Discussionmentioning

confidence: 99%

“…Myocarditis is a less common complication (affecting 7% of patients) and can be associated with pericarditis (31% in a recent overview) ( 5 ). Cardiac involvement is more frequent in young men (38%) (mean age: 32 years) and is often present at diagnosis (65%).…”

Section: Discussionmentioning

confidence: 99%

Acute Myocarditis Revealing Adult-Onset Still’s Disease

et al. 2021

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A 34-year-old man presented with fever, palpitations, maculopapular rash, pharyngitis, left cheilitis, and bilateral gonalgia. High-sensitivity troponin I concentration was 4,900 ng/l. Transthoracic echocardiogram revealed reduced global longitudinal strain. Cardiac magnetic resonance imaging showed acute myocarditis. Adult-onset Still’s disease was diagnosed, and treatment with intravenous corticosteroids and tocilizumab was initiated. ( Level of Difficulty: Beginner. )

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“…AOSD is a non-hereditary, non-organ specific, polygenic autoinflammatory disease that affects young adults in a bimodal distribution with an average age of 15–25 and 36–46 years old and an incidence of 0.16–0.4/100,000 individuals ( 180 ). Its pathogenic mechanism involves a genetic background with triggering factors that generate a dysregulated immune activation with overproduction of inflammatory cytokines, principally IL-1, IL-6, and IL-18, and a deficiency of anti-inflammatory mechanisms ( 181 ).…”

Section: Cmr Techniquementioning

confidence: 99%

“…Pericarditis can evolve until tamponade, but it is rare. Other described forms of cardiac involvement are endocarditis and myocarditis, which are present in 7% of cases ( 180 , 182 , 183 ).…”

Section: Cmr Techniquementioning

confidence: 99%

Cardiac Magnetic Resonance in Rheumatology to Detect Cardiac Involvement Since Early and Pre-clinical Stages of the Autoimmune Diseases: A Narrative Review

Sierra-Galan

Bhatia

Alberto-Delgado

et al. 2022

Front. Cardiovasc. Med.

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Autoimmune diseases (ADs) encompass multisystem disorders, and cardiovascular involvement is a well-known feature of autoimmune and inflammatory rheumatic conditions. Unfortunately, subclinical and early cardiovascular involvement remains clinically silent and often undetected, despite its well-documented impact on patient management and prognostication with an even more significant effect on severe and future MACE events as the disease progresses. Cardiac magnetic resonance imaging (MRI), today, commands a unique position of supremacy versus its competition in cardiac assessment and is the gold standard for the non-invasive evaluation of cardiac function, structure, morphology, tissue characterization, and flow with the capability of evaluating biventricular function; myocardium for edema, ischemia, fibrosis, infarction; valves for thickening, large masses; pericardial inflammation, pericardial effusions, and tamponade; cardiac cavities for thrombosis; conduction related abnormalities and features of microvascular and large vessel involvement. As precise and early detection of cardiovascular involvement plays a critical role in improving the outcome of rheumatic and autoimmune conditions, our review aims to highlight the evolving role of CMR in systemic lupus erythematosus (SLE), antiphospholipid syndrome (APS), rheumatoid arthritis (RA), systemic sclerosis (SSc), limited sclerosis (LSc), adult-onset Still's disease (AOSD), polymyositis (PM), dermatomyositis (DM), eosinophilic granulomatosis with polyangiitis (EGPA) (formerly Churg-Strauss syndrome), and DRESS syndrome (DS). It draws attention to the need for concerted, systematic global interdisciplinary research to improve future outcomes in autoimmune-related rheumatic conditions with multiorgan, multisystem, and cardiovascular involvement.

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Myocarditis in Adult-Onset Still’s Disease: Case-Based Review

Cited by 16 publications

References 63 publications

Flagellate dermatoses associated with myocarditis in Adult-onset Still's disease

Flagellate dermatoses associated with myocarditis in Adult-onset Still's disease

Acute Myocarditis Revealing Adult-Onset Still’s Disease

Cardiac Magnetic Resonance in Rheumatology to Detect Cardiac Involvement Since Early and Pre-clinical Stages of the Autoimmune Diseases: A Narrative Review

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