Myocardial Recovery Following Left Ventricular Assist Device Therapy

Navaratnarajah, Manoraj; Ibrahim, Michael; Yacoub, Magdi H.; Terracciano, Cesare M.

doi:10.5772/23823

Cited by 1 publication

(1 citation statement)

References 123 publications

(76 reference statements)

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“…(b) Bridge to Recovery: This type of treatment is typically intended for patients whose heart condition may improve as a result of the LVAD support. It was observed [5][6][7][8][9][10] that some patients can be weaned from the LVAD as their hemodynamic and physiological changes indicate recovery of the heart muscle. As in the case of the bridge-to-transplant treatment, the LVAD support in this case is also temporary and is kept until recovery occurs.…”

Section: Introductionmentioning

confidence: 99%

An Engineering Analysis of the Aortic Valve Dynamics in Patients with Rotary Left Ventricular Assist Devices

Faragallah

Simaan

2013

Journal of Healthcare Engineering

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The use of a rotary Left Ventricular Assist Device (LVAD) as a bridge-to-recovery treatment is gaining considerable attention in the LVAD research community. Using a mathematical model of the cardiovascular-LVAD system, this paper intends to define the critical control parameters in terms of power and rotational speed of the LVAD to ensure normal dynamics of the aortic valve for different levels of patient's activity and severity of heart failure. The effects of permanent closure of the aortic valve on the hemodynamics of the patient and the pump flow characteristics, if the critical control values are exceeded, are also examined. Additionally, LVAD power and speed control parameters that yield a given percentage of the cardiac cycle during which the aortic valve remains open are examined indicating that the severity of the heart failure is a very important factor in deciding the appropriateness of the LVAD as a bridge-to recovery treatment.

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