Myocardial protection in operations requiring more than 2 h of aortic cross-clamping

Bar-El, Yaron; Adler, Zvi; Kophit, Arcadi; Kertzman, Victor; Sawaed, Shtiwi; Ross, Andre; Cohen, Oved; Milo, Simcha

doi:10.1016/s1010-7940(99)00025-1

Cited by 21 publications

(14 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Atrial fibrillation is observed in 7 to 40% of the cases after coronary bypass surgery [30,31]. Paroxysmal AF attacks emerged in 53% of our cases.…”

Section: Discussionmentioning

confidence: 85%

See 1 more Smart Citation

Ischemia-modified albumin use as a prognostic factor in coronary bypass surgery

Kanko

Yavuz

Duman

et al. 2012

J Cardiothorac Surg

View full text Add to dashboard Cite

BackgroundVarious types of markers have been used so far in order to reveal myocardial perfusion defect. However, these markers usually appear in the necrosis phase or in the late stage. Having been the focus of various investigations recently, ischemia-modified albumin (IMA) is helpful in establishing diagnosis in the early stages of ischemia, before necrosis develops.Methods and Results30 patients that underwent only coronary bypass surgery due to ischemic heart disease within a specific period of time have been included in the study. IMA levels were studied in the preoperative, intraoperative, and postoperative periods. The albumin cobalt binding assay was used for IMA determination. Hemodynamic parameters (atrial fibrillation, the need for inotropic support, ventricular arrhythmia) of the patients in the postoperative stage were evaluated. Intraoperative measurement values (mean ± SD) of IMA (0.67677 ± 0.09985) were statistically significantly higher than those in the preoperative (0.81516 ± 0.08894) and postoperative (0.70477 ± 0.07523) measurements. Considering atrial fibrillation and need for inotropics, a parallelism was detected with the levels of IMA.ConclusionsIMA is an early-rising marker of cardiac ischemia and enables providing a direction for the treatment at early phases.

show abstract

“…Atrial fibrillation is observed in 7 to 40% of the cases after coronary bypass surgery [30,31]. Paroxysmal AF attacks emerged in 53% of our cases.…”

Section: Discussionmentioning

confidence: 85%

“…If the duration of cross-clamping is longer than 90 minutes, the need for inotropics increases [31]. In 23 (76%) of our cases, a need for an inotropic (7-15 microgram/kg/min dopamine) developed.…”

Section: Discussionmentioning

confidence: 94%

Ischemia-modified albumin use as a prognostic factor in coronary bypass surgery

Kanko

Yavuz

Duman

et al. 2012

J Cardiothorac Surg

View full text Add to dashboard Cite

show abstract

“…Compared with consultants, trainees' cases experienced longer aortic cross-clamp times even after propensity-score matching, reflecting the inherent learning curve associated with surgery in general, and perhaps mitral surgery in particular. However, these differences have not been shown to necessarily increase mortality rates [11][12][13]. Indeed, no difference in 30-day mortality was observed amongst the matched pairs.…”

Section: Discussionmentioning

confidence: 88%

Training in mitral valve surgery need not affect early outcomes and midterm survival: a multicentre analysis

Shi

Yap

Dinh

et al. 2011

European Journal of Cardio-Thoracic Surgery

View full text Add to dashboard Cite

show abstract

“…We believe that inclusion bias might explain this, as patients with the greatest impairment of LV function are unlikely to undergo surgery due to the prohibitive mortality. Secondly, improvements in myocardial protection with the use of retrograde room temperature cardioplegia 14,15 have been shown to reduce early morbidity. This coupled with advances in medical care of patients with LV dysfunction, such as the routine use of ACE inhibitors 16 and more recently beta blockade 17 would be expected to alter the natural history of the disease, improving survival.…”

Section: Discussionmentioning

confidence: 99%