Myocardial Perfusion Imaging Is a Strong Predictor of Death in Women

Abstract

SPECT-MPI added significant incremental prognostic information to clinical and left ventricular functional variables while enhancing the ability to classify this Brazilian female population into low- and high-risk categories of all-cause mortality.

Prognosis in patients with suspected or known ischemic heart disease and normal myocardial perfusion: Long-term outcome and temporal risk variations

“…Indeed, their risk equated that of diabetic patients, whereas women had a risk similar to non-diabetic patients. A low risk of death and cardiac events in women with normal MPS has previously been reported, 6,12 even in women with a high pre-test likelihood of disease. 27 However, others described that in the presence of DM or CAD women had prognoses equally severe to that of men.…”

“…11 Furthermore, ethnic and socioeconomic differences have been pinpointed. 12,13 Recently, reports on long-term outcome after (normal) MPS have also been emerging. 14,15 Despite this wealth of information, gaps in our knowledge base do still remain.…”

Role of Noninvasive Testing in the Clinical Evaluation of Women With Suspected Ischemic Heart Disease

“…139,[149][150][151][152][153][154] The American Society of Nuclear Cardiology published an information statement on the use of stress MPI in women, 155 and a detailed review of the prognostic evidence base with stress MPI was published recently. 139 Data support that stress myocardial perfusion and ventricular function measurements provide independent and incremental information over and above clinical history and ECG data.…”

Net Reclassification Improvement and Integrated Discrimination Improvement

“…Only a handful of recent nuclear cardiology publications have applied this approach. [12][13][14] The present study by Candell-Riera et al 6 can be added to this small group of important studies.…”