Myocardial infarction in a patient with left ventricular noncompaction: a case report

Toufan, Mehrnoush; Shahvalizadeh, Roya; Khalili, Majid

doi:10.2147/ijgm.s28902

Cited by 8 publications

(4 citation statements)

References 29 publications

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“…To the best of our knowledge, this is the first case of LVNC associated with anomalous coronary artery origin and STEMI reported in the literature. Seven cases of acute myocardial infarction (AMI) have been reported in patients with LVNC [ 14 , 15 , 16 , 17 , 18 , 19 , 20 ], five of them were anterior STEMI in male patients aged between 45 and 63 years [ 14 , 16 , 17 , 18 , 19 ], and one was an AMI in a patient with three-vessels disease treated with coronary artery bypass graft (CABG) [ 20 ]. Panduranga et al reported a case of a patient with LVNC and STEMI, non-dyslipidemic, and hypothesized that a single gene responsible for both myocardial development and coronary endothelium could be involved in the pathogenesis of LVNC and at the same time predisposition to coronary atherosclerosis [ 14 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Left Ventricular Non-Compaction with Coronary Artery Anomaly Complicated by ST-Elevation Myocardial Infarction and Subcutaneous Defibrillator Implantation

Prandi

Illuminato

Galluccio

et al. 2022

IJERPH

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Left ventricular non-compaction (LVNC) is a rare congenital cardiomyopathy caused by arrest of normal endomyocardial embryogenesis and characterized by the persistence of ventricular hypertrabeculation, isolated or associated to other congenital defects. A 33-year-old male, with family history of sudden cardiac death (SCD), presented to our ER with typical chest pain and was diagnosed with anterior STEMI. Coronary angiography showed an anomalous origin of the circumflex artery from the right coronary artery and a critical stenosis on the proximal left anterior descending artery, treated with primary percutaneous coronary intervention. The echocardiogram documented left ventricular severe dysfunction with lateral wall hypertrabeculation, strongly suggestive for non-compaction, confirmed by cardiac MRI. At 3 months follow up, for the persistence of the severely depressed EF (30%) and the family history for SCD, the patient underwent subcutaneous ICD (sICD) implantation for primary prevention. To the best of our knowledge, this is the first case of LVNC associated with anomalous coronary artery origin and STEMI reported in the literature. Arrhythmias are common in LVNC due to endocardial hypoperfusion and fibrosis. sICD overcomes the risks of transvenous ICD, and it is a valuable option when there is no need for pacing therapy for bradycardia, cardiac resynchronization therapy and anti-tachycardia pacing.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Left Ventricular Non-Compaction with Coronary Artery Anomaly Complicated by ST-Elevation Myocardial Infarction and Subcutaneous Defibrillator Implantation

Prandi

Illuminato

Galluccio

et al. 2022

IJERPH

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“…ИМ был заподозрен клинически (уровень тропонина I в венозной крови 33,900 и >50,000 нг/мл в динамике) и подтвержден при патологоанатомическом исследовании. В литературе представлены описания сочетания НМЛЖ и подострого или острого ИМ 1 типа атерогенного генеза у пациентов старше 45 лет [41][42][43][44][45]. Güvenç TS, et al (2012) описывают клинический случай эмболического ИМ при интактных коронарных артериях по данным КАГ у 20-летнего мужчины с НМЛЖ [46].…”

Section: Discussionunclassified

Mixed phenotype cardiomyopathy, associated with DSP genetic variant: a case report and literature review.

et al. 2020

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“…A comprehensive echocardiographic study including M-mode, two-dimensional echocardiography, and Doppler echocardiographic measurements, was performed in all patients using an ultrasound system (Vivid 7; GE Healthcare, Horten, Norway) operated by an experienced cardiologist blinded to the multidetector CT findings. 15 – 18 The presence of mitral valve stenosis was defined as restriction of leaflet motion leading to a transmitral diastolic gradient. The severity of mitral stenosis was classified according to American College of Cardiology/American Heart Association guidelines.…”

Section: Methodsmentioning

confidence: 99%

Relationship between incidentally detected calcification of the mitral valve on 64-row multidetector computed tomography and mitral valve disease on echocardiography

Toufan¹,

Javadrashid²,

Paak³

et al. 2012

IJGM

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BackgroundMitral valve calcification is often incidentally detected on chest computed tomography (CT) scans obtained for a variety of noncardiac indications. In this study, we evaluated the association between mitral valve calcification incidentally detected on chest CT and the presence and severity of mitral valve disease on echocardiography.MethodsOf 760 patients undergoing 64-row multidetector CT of the chest, 50 with mitral valve calcification and 100 controls were referred on for echocardiography. Calcifications of the mitral valve leaflet and annulus were assessed for length, Agatston score, and site, and were compared with echocardiographic findings.ResultsMitral valve calcification was noted in 59 (7.7%) patients on multidetector CT. Fifty of these patients were assessed by echocardiography, and 32 (64%) were found to have mitral annular calcification. Nine patients (18%) had posterior mitral valve leaflet calcification, and both mitral valve leaflet and annular calcification were detected in nine (18%) cases. Nine (18%) patients had mild, three (6%) had moderate, and one (2%) had severe mitral stenosis. None of the patients with isolated mitral annular calcification had mitral stenosis; however, all the patients with mitral stenosis showed mitral valve leaflet calcification with or without mitral annular calcification (P < 0.001). Moreover, patients with mitral stenosis had a larger mitral calcification length and greater Agatston scores in comparison with those without mitral stenosis (P = 0.001). While 31 patients (62%) with mitral calcification had mitral regurgitation on echocardiography, 21 (21%) in the control group showed mitral regurgitation (P = 0.001).ConclusionMitral valve leaflet calcification, with or without annular calcification, may be an indicator of mitral stenosis. Mitral calcification can also be considered as an indicator for mitral regurgitation in general. Therefore, patients with mitral valve calcification detected incidentally on chest CT scan may benefit from functional assessment of the valve using echocardiography.

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Myocardial infarction in a patient with left ventricular noncompaction: a case report

Cited by 8 publications

References 29 publications

A Rare Case of Left Ventricular Non-Compaction with Coronary Artery Anomaly Complicated by ST-Elevation Myocardial Infarction and Subcutaneous Defibrillator Implantation

A Rare Case of Left Ventricular Non-Compaction with Coronary Artery Anomaly Complicated by ST-Elevation Myocardial Infarction and Subcutaneous Defibrillator Implantation

Mixed phenotype cardiomyopathy, associated with DSP genetic variant: a case report and literature review.

Relationship between incidentally detected calcification of the mitral valve on 64-row multidetector computed tomography and mitral valve disease on echocardiography

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