Myocardial Infarction Complicated by Acute Ischemic Stroke due to Alteplase

Abstract

The early reperfusion therapy with tissue plasminogen activator (tPA) for acute myocardial infarction (MI) in the first 12 hours outweighs its risks. One of the known major complications of tPA is intracerebral hemorrhage (ICH). A rare and unexpected complication following the administration of thrombolytic treatment is acute ischemic stroke. Our case study is a 54-year-old lady with an acute myocardial infarction who received antifibrinolytic medication and paradoxically experienced an abrupt ischemic stroke. This case highlights a rare but dangerous complication of an acute ischemic stroke.