Abstract:The myocardium of molluscs exhibits profound anoxia tolerance, however the cellular mechanisms underlying heart performance during normoxia and anoxia are not well understood. In the present study we investigated the role of the sarcoplasmic reticulum (SR) during normoxia and chemical anoxia (2 mM sodium cyanide) in electrically paced ventricle preparations from the common cockle (Cerastoderma edule) at ~19°C. Acute anoxia caused a substantial increase in resting tension but did not significantly affect the fo… Show more
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