Myocardial-coronary fusion imaging with positron emission tomography and computed tomography: Benchmarking and slingshotting

Abstract

If there is knowledge, it lies in the fusion of the book and the street Louis ''Studs'' Terkel

Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2020: positron emission tomography, computed tomography, and magnetic resonance

“…Color-coded images were then generated resembling 3-dimensional fractional flow reserve (FFR). 19 , 20 …”

Network Medicine: A Clinical Approach for Precision Medicine and Personalized Therapy in Coronary Heart Disease

“…CCTA evolved not only to reduce radiation exposure, but also to optimize image acquisition, achieving more spatial and contrast resolution [28][29][30][31] . The real revolution for non-invasive anatomical evaluation of the coronary tree has been achieved only recently, with the introduction of "fourth generation" wide-volume scanners, with up to 16 cm of cranialcaudal coverage in a single rotation, enabling wholeheart coverage at one acquisition time point (within one heartbeat or volume).…”

“…The real revolution for non-invasive anatomical evaluation of the coronary tree has been achieved only recently, with the introduction of "fourth generation" wide-volume scanners, with up to 16 cm of cranialcaudal coverage in a single rotation, enabling wholeheart coverage at one acquisition time point (within one heartbeat or volume). It eliminates "stair-step" or misalignment artifacts and provides uniform attenuation when evaluating the coronary arteries or measuring contrast attenuation gradients across atherosclerotic lesions 29) . Furthermore, radiation doses are lower with wide-area detector scanners because of shorter to individualize/focus treatments and develop new diagnostic tools, useful in primary prevention, and in subjects in early stages of disease, as well as for secondary prevention 6,16) .…”

“…1I and 1J). This combined technology allows detection and quantification of the burden of calcified and non-calcified plaques, quantification of vascular activity and endothelial function, identification of flow-limiting coronary stenosis, and, potentially, identification of high-risk plaques 51) (Fig. 1K, 1L and 1M).…”

“…1K, 1L and 1M). PET/CT is today well established in clinical routine imaging 51) . PET/MR represents a new integrated protocol for simultaneous evaluation of viability, perfusion, morphological and functional imaging, thus eliminating ionizing radiation and improving tissue contrast 52) .…”