Myocardial Boring for the Ischemic Heart

History of Surgical Treatment of Ischemic Heart Disease?Pre-?Coronary Bypass Grafting? Era

“…Sen et al 69 (1956) explored the reptilian heart, in which the myocardium is supplied chiefly by channels that arise directly from the cavities of the heart, with only a rim at the heart's periphery supplied by coronary vessels and published an experimental study of transmyocardial acupuncture, also termed as the “snake heart operation.” They reported their encouraging results in 1968 70 . Similarly, Wakabayashi 71 (1967) suggested myocardial boring. These procedures would be the forerunner of transmyocardial laser revascularization.…”

Myocardial Blood Flow and Alterations of LDH Isoenzymes in Infarcted Heart Muscle and After Transmural Punctures

“…Trying to create the reptilian myocardial vascular pattern in the mammalian experimental animal, Sen and co-workers [3] of Bombay, reported a mortality rate of 25%> within 2 weeks in animals in which transmyocardial acupuncture had been performed, together with ligation of the anterior descending coronary artery as compared to a mortali ty rate of 75% in controls. This method has been investigated experimentally by various authors [1,2,4,6,7] with controversial results. The purpose of this study was to evaluate the feasibility of this method by blood flow measurements and es timation of myocardial LDH enzyme alteration in the infarcted area.…”