Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Associated Glomerulonephritis with Membranous Nephropathy in Remission.

Membranous Glomerulonephritis with ANCA-Associated Necrotizing and Crescentic Glomerulonephritis

“…The occurrence of ANCA-associated NCGN and primary MGN in the same patient is rare, with only a handful of reports in the literature (5)(6)(7)(8)(9)(10). Herein, we detail the clinical, pathologic, and outcome data of 14 patients with this rare dual glomerulopathy and review the previously reported cases.…”

Coexistent Membranous Nephropathy with Doubly ANCA-Associated Crescentic Glomerulonephritis: A Case Report and Review of Literature

“…Coexistent MN and PNCGN is a rare occurrence, with only 25 reported cases in the English literature in which clinical and pathologic findings are detailed [9,[12][13][14][15][16][17][18]. Thirteen patients had P-ANCA by indirect immune fluorescent (IIF) staining, seven of whom were tested with ELISA and found to have MPO-ANCA.…”

“…Patients with both MN and PNCGN are likely to have heavier proteinuria than patients with PNCGN alone. All of 25 reported cases with urine output had proteinuria [9,[12][13][14][15][16][17][18]. From the recent report, the mean 24-h urine protein for these patients was 6.5 g, compared with 1.7 to 2.5 g in patients with ANCA disease alone [22].…”

“…Among the 25 reported cases of MN and PNCGN, induction therapy consisted of prednisone and CY in 20 patients, prednisone and azathioprine in one patient, and prednisone alone in one patient. One patient received mycophenolate mofetil and two patients also received plasmapheresis [9,[12][13][14][15][16][17][18].…”

A case presenting with the possible relationship between myeloperoxidase–antineutrophil cytoplasmic antibody-associated glomerulonephritis and membranous changes of the glomerular basement membrane

“…A dual presentation of MPO-ANCA-associated glomerulonephritis with MN is rare [5][6][7][8][9][10][11]. We report here a rare case of MPO-ANCA-associated glomerulonephritis with MN suspected to be a secondary form.…”