Myeloma and Pernicious Anaemia

The Occurrence of Benign, Essential Monoclonal (M Type), Non‐macromolecular Hyperglobulinemia and its Differential Diagnosis

“…This patient has a high titre of thyroid antibodies, very low B,, values and a Schilling test of 7 yo absorption of BIZ. Her anemia was treated in a paper by Larsson (7). I t seems almost certain that this is an instance of myeloma even though the high titre of thyroid antibodies is an unusual finding.…”

Familial Occurrence of M‐components

“…Myeloma and asyniptomatic M-component occurring in !he .Tame family has been reported in couples of siblings in three families (13,23). (The asymptomatic M-components belonged to the types yG (13,23) and yM (23).)…”

“…Myeloma and asyniptomatic M-component occurring in !he .Tame family has been reported in couples of siblings in three families (13,23). (The asymptomatic M-components belonged to the types yG (13,23) and yM (23).) The clue to the findings of Spengler et al (23) was a systematic investigation of 110 relatives of 22 individuals with M-components of different kinds (myeloma 14, macroglobulinaemia Waldenstrorn six and asymptomatic M-component two).…”

The Occurrence of Serological “Antibody” Reagins or Similar γ‐Globulins in Conditions with Monoclonal Hypergammaglobulinemia, such as Myeloma, Macroglobulinemia etc.

“…She has pernicious anemia and this problem has been treated by S.O. Larsson in a recent publication (9). We have followed her y-globulin values, and her general status since 1956 has been quite unchanged (nearly 6 years).…”