Myelolipomas of the Liver in Captive Wild Felidae

Lombard, Louise S.; Fortna, H. M.; Garner, F. M.; Brynjolfsson, Gissur

doi:10.1177/030098586800500204

Cited by 18 publications

(21 citation statements)

References 3 publications

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“…multiple hepatic myelolipomas (7,9,13,16) and multiorganic myelolipomas (9). In conclusion, our case of a common marmoset is the first report of myelolipomas occurring simultaneously in the adrenal gland and liver of an animal.…”

mentioning

confidence: 52%

Spontaneous Adrenal and Hepatic Myelolipomas in the Common Marmoset

et al. 1994

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mentioning

confidence: 52%

Spontaneous Adrenal and Hepatic Myelolipomas in the Common Marmoset

et al. 1994

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“…Only a few cases have been reported in other mammals, and there has apparently been no prior report of this tumor in a simian primate. Liver and splenic involvement has been reported in the cheetah and Siberian tiger [Lombard et al, 1968;Cordy & Bostrom, 19781 and in the domestic cat [Gourley et al, 1971;Sanders & Langham, 1972;Ikede & Downey, 19721 and a subcutaneous myeloliposarcoma has been described in the potto [Bingham et al, 19761. A renal myelolipoma in a 64-year-old man has been reported [Beraha et al, 19741 and that report closely resembles the present case.…”

Section: Discussionmentioning

confidence: 99%

A juxtarenal myelolipoma in a cottontop marmoset (Saguinus oedipus): A case report

Stein

Smallwood

Tangner

et al. 1982

American J Primatol

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A myelolipoma was surgically removed from the abdomen of a 15-year-old female cottontop marmoset (Saguinus oedipus). Because of its close adherence to the right kidney, a unilateral nephrectomy was performed. The post-surgical recovery was uneventful. A myelolipoma is a circumscribed mass of bone marrow elements embedded in mature adipose tissue. These masses have been reported in the adrenal glands, paravertebral tissue, intrathoracic tissues, and mesentery of man. A similar condition has been observed in the liver and spleen of both captive and wild felidae. This report documents the first observation of this tumor-like condition in nonhuman primates with the possible exception of a subcutaneous myeloliposarcoma in a potto.

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“…These well-vascularized extramedullary masses may be encapsulated or may blend into surrounding tissues. Myelolipomas have been reported in the spleen [6] and liver [3, 41 of the domestic cat, the spleen [2] and liver [5, 71 of the cheetah (Acinonyxjuhalus) and the liver of the Siberian tiger (Felis tigris longipilis) [5]. A myeloliposarcoma has been reported in the inguinal region of a potto (Perodictictu potlo) [I].…”

Section: A Zimmer and E L Stairmentioning

confidence: 99%

“…These two dogs had masses which represented opposite extremes in ratios of adipose to hematopoietic cells. Various cell ratios between masses of different animals have been reported [ 5 ] , and therefore would not be considered unusual in dogs. It is interesting, though probably not significant, that these two myelolipomas occurred in the same breed.…”

Section: A Zimmer and E L Stairmentioning

confidence: 99%

Splenic Myelolipomas in Two Dogs

Zimmer¹,

Stair²

1983

Vet Pathol

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Myelolipomas are benign neoplasm-like nodules composed of various quantities of mature adipose cells and hematopoietic cells. These well-vascularized extramedullary masses may be encapsulated or may blend into surrounding tissues. Myelolipomas have been reported in the spleen [6] and liver [3, 41 of the domestic cat, the spleen [2] and liver [5, 71 of the cheetah (Acinonyxjuhalus) and the liver of the Siberian tiger (Felis tigris longipilis) [5]. A myeloliposarcoma has been reported in the inguinal region of a potto (Perodictictu potlo) [I]. There are no reports of this condition in dogs.Myelolipomas were found in two dogs. Dog A was a 12-year-old, intact female, miniature schnauzer which had no clinical signs associated with the splenic mass. The mass measured 7 cm in diameter, was tan and had a fat-like appearance on the cut surface. Dog B was a 12-year-old, spayed miniature schnauzer with a history of abdominal enlargement. The splenic mass measured 6 X 6 x 8 cm and was mottled red-to-tan and soft.Microscopically, masses from both dogs had similar components but vaned in the ratio of adipose cells to hematopoietic cells. The mass from dog A consisted of small groups of relatively mature erythroid and myeloid cells interspersed between a large number of mature adipose cells ( fig. I). No capsule was evident, but the mass was well demarcated from the surrounding parenchyma. Massive extramedullary hematopoiesis, both erythroid and myeloid, widely dispersed the adipose wells in the splenic mass from dog B (fig. 2). The cell population consisted of cells in all stages of differentiation-most were relatively immature. The nodule was unencapsulated and blended into the surrounding splenic parenchyma. Multiple foci of nodular hyperplasia were observed in the spleen. These two dogs had masses which represented opposite extremes in ratios of adipose to hematopoietic cells. Various cell ratios between masses of different animals have been reported [ 5 ] , and therefore would not be considered unusual in dogs. It is interesting, though probably not significant, that these two myelolipomas occurred in the same breed. Myelolipomas previously had been described only in domestic and wild Felidae. This report demonstrates that dogs also can develop myelolipomas.

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Myelolipomas of the Liver in Captive Wild Felidae

Cited by 18 publications

References 3 publications

Spontaneous Adrenal and Hepatic Myelolipomas in the Common Marmoset

Spontaneous Adrenal and Hepatic Myelolipomas in the Common Marmoset

A juxtarenal myelolipoma in a cottontop marmoset (Saguinus oedipus): A case report

Splenic Myelolipomas in Two Dogs

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