“…Furthermore, in response to these stressors, astrocytes increase the expression of other members of the heat shock protein family, including Hsp90, Hsp60, Hsp27, heme oxygenase-1 (hsp32), and alphaB-crystallin (Chopra et al, 1995;Bajramovic et al, 2000;Bidmon et al, 2001;Salvador-Silva et al, 2001;Acarin et al, 2002;Businaro et al, 2002;Fauconneau et al, 2002;Bidmon et al, 2004;Dabir et al, 2004). Although it has been suggested for some time, only recently it has become generally accepted that many cells, including astrocytes can release Hsp/c70 in response to stress both in vitro and in vivo (Tytell et al, 1986;Hightower and Guidon, 1989;Edbladh et al, 1994;Sheller et al, 1995Sheller et al, , 1998Guzhova et al, 2001;de Freitas et al, 2002;Dybdahl et al, 2002;Broquet et al, 2003;Robinson et al, 2005).…”