Mycotic iliac aneurysm associated with Burkholderia pseudomallei

Melioidosis in Africa: Should we be Looking more Closely?

“…Other cases of human melioidosis were more recently reported from Madagascar [9], Nigeria [11] and Malawi [12]. Imported cases from Africa to Europe were reported in France (country of patient origin remaining unclear) [29], Spain (imported from the Gambia [10] and Madagascar [13]) and the UK (imported from Nigeria) [30]. Most recently, the first molecular sequence typing (MLST) confirmed case of melioidosis in Central Africa was reported in a female farmer with diabetes in Gabon [20].…”

“…Few studies report culture results to finally confirm a diagnosis of melioidosis. Polymerase chain reaction (PCR) based confirmation of colonies was used in only five out of the 13 human melioidosis case reports [9][10][11][12][13]20,29]. MLST and whole-genome sequencing (WGS) used in the most recent case reports [11][12][13]20] is the method of choice to further characterize B. pseudomallei strains [33].…”

Clinical, Environmental, and Serologic Surveillance Studies of Melioidosis in Gabon, 2012–2013

“…Only 4 of the 13 melioidosis cases acquired by humans in Africa and reported in the literature have been PCR confirmed ( 9 – 12 , 29 – 34 ). We show with phylogenetic analysis that the newly identified patient isolate Gb100 groups with a B. pseudomallei isolate from a patient from Spain who had traveled across West Africa and Madagascar ( 12 ).…”

Mycotic aneurysm caused byBurkholderia pseudomalleiin a previously healthy returning traveller

“…To the best of our knowledge, only very few reports exist of mycotic aneurysms by B. pseudomallei in returning travellers without any established risk factors,14 15 but mycotic aneurysms have been described in travellers with risk factors16 and in endemic areas such as Australia,12 Southeast Asia4 8 17 and Brazil 7…”