Mycotic abdominal aortic aneurysm associated with myelodysplastic syndrome (MDS): Report of a case

Abstract

A 59-year-old man, who manifested lower back pain, was admitted with sepsis and disseminated intravascular coagulation (DIC). A computed tomographic scan showed a slight thickening of the abdominal aortic wall. A blood examination revealed pancytopenia. Myelodysplastic syndrome was diagnosed after bone marrow aspiration and a chromosome analysis. Sepsis due to a Staphylococcus aureus infection and DIC subsided after medical treatment; however, an aortobifemoral bypass was performed upon the detection of a localized rupture of a mycotic abdominal aortic aneurysm 1 month later. The patient is still alive 2 years after operation despite the presence of a hematological disorder.

Aortic Valve Replacement in a Patient With Myelodysplastic Syndrome and Interstitial Pneumonia

“…We conclude that G-CSF may be unnecessary for infection-free cardiovascular surgery in MDS patients. On the other hand, Yamamoto et al reported a case of mycotic abdominal aortic aneurysm in a diabetic patient and use of G-CSF before surgery, 9 which we thought was rational use in that case because the patient already had a severe infection.…”

“…Myelodysplastic syndrome (MDS) is clinical condition with pancytopenia caused by dysplasia of the bone marrow. Because the patients with MDS has risks of bleeding and infection, 1,[5][6][7][8][9] cardiac surgery using extracorporeal circulation (ECC) increases those risks, which affect morbidity and mortality. 2 Interstitial pneumonia is also a risk factor in cardiac surgery, because it exacerbates lung function after surgery, and steroid therapy for interstitial pneumonia associated with scleroderma is necessary, but that also increases the morbidity and mortality.…”