Mycostop - A Novel Biofungicide Based on Streptomyces Bacteria

Lahdenperä, M.-L.; Simon, Elis Daiani Timm; Uoti, Juhani

doi:10.1016/b978-0-444-88728-3.50048-2

Cited by 44 publications

(20 citation statements)

References 2 publications

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“…Prominent exceptions are the Streptomyces species involved in the specific suppressiveness of field soils to common scab of potato after long-term potato cultivation (reviewed by Weller et al, 2002) and Streptomyces griseoviridis, a major component of the commercial biofungicide MYCOSTOP (Lahdenperä et al, 1991). The latter strain produces a candicidin polyene macrolide antibiotic, genes for the synthesis of which are widely distributed among the Actinobacteria.…”

Section: Discussionmentioning

confidence: 99%

Microbial and biochemical basis of a Fusarium wilt-suppressive soil

et al. 2015

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Crops lack genetic resistance to most necrotrophic pathogens. To compensate for this disadvantage, plants recruit antagonistic members of the soil microbiome to defend their roots against pathogens and other pests. The best examples of this microbially based defense of roots are observed in disease-suppressive soils in which suppressiveness is induced by continuously growing crops that are susceptible to a pathogen, but the molecular basis of most is poorly understood. Here we report the microbial characterization of a Korean soil with specific suppressiveness to Fusarium wilt of strawberry. In this soil, an attack on strawberry roots by Fusarium oxysporum results in a response by microbial defenders, of which members of the Actinobacteria appear to have a key role. We also identify Streptomyces genes responsible for the ribosomal synthesis of a novel heat-stable antifungal thiopeptide antibiotic inhibitory to F. oxysporum and the antibiotic’s mode of action against fungal cell wall biosynthesis. Both classical- and community-oriented approaches were required to dissect this suppressive soil from the field to the molecular level, and the results highlight the role of natural antibiotics as weapons in the microbial warfare in the rhizosphere that is integral to plant health, vigor and development.

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Section: Discussionmentioning

confidence: 99%

Microbial and biochemical basis of a Fusarium wilt-suppressive soil

et al. 2015

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“…and Alternaria spp. (Lahdenperä et al 1991). In addition to their ability to inhibit plant pathogens, actinomycete bacteria appear to be of great importance among the microbial flora of the rhizosphere.…”

Section: Introductionmentioning

confidence: 99%

Evidences of biological control capacities of Streptomyces spp. against Sclerotium rolfsii responsible for damping-off disease in sugar beet (Beta vulgaris L.)

Errakhi

Bouteau

Lebrihi

et al. 2007

World J Microbiol Biotechnol

126

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Ten antibiotic-producing Streptomyces spp. isolated from Moroccan soils were evaluated for their ability to inhibit in vitro Sclerotium rolfsii development. Four isolates having the greatest pathogen inhibitory capabilities were subsequently tested for their ability to inhibit sclerotial germination in sterile soil. This test was carried out by using biomass inoculum, culture filtrate, and spore suspension of the isolates as treatment. Treatment with biomass inoculum and culture filtrate gave the highest inhibition of sclerotia. Biological control tests against Sclerotium rolfsii damping-off of sugar beet seeds showed that the selected Streptomyces isolates reduced significantly the disease severity, the J-2 isolate being the more potent. In addition, treatment with the isolate J-2 resulted in a significant increase (P £ 0.05) in seedling development compared to the control. All antagonistic Streptomyces selected here were able to grow in the rhizosphere soil from infected sugar beet culture.

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“…(3,34,58,61). Despite the development of a successful biocontrol product from an isolate of Streptomyces griseoviridis (33) from such a peat, the microbial and physical characteristics of peats that are associated with suppressiveness are not well defined. The level of organic decomposition of the peat, the development of an active microbial biomass, and the microbial composition of such a biomass (4,11,12,25) have all been implicated as important factors in determining suppressiveness.…”

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confidence: 99%

Differences in Microbial Activity and Microbial Populations of Peat Associated with Suppression of Damping-Off Disease Caused by Pythium sylvaticum

Hunter

Petch

Calvo-Bado

et al. 2006

Appl Environ Microbiol

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The microbiological characteristics associated with disease-suppressive peats are unclear. We used a bioassay for Pythium sylvaticum-induced damping-off of cress seedlings to identify conducive and suppressive peats. Microbial activity in unconditioned peats was negatively correlated with the counts of P. sylvaticum at the end of the bioassay. Denaturing gradient gel electrophoresis (DGGE) profiling and clone library analyses of small-subunit rRNA gene sequences from two suppressive and two conducive peats differed in the bacterial profiles generated and the diversity of sequence populations. There were also significant differences between bacterial sequence populations from suppressive and conducive peats. The frequencies of a number of microbial groups, including the RhizobiumAgrobacterium group (specifically sequences similar to those for the genera Ochrobactrum and Zoogloea) and the Acidobacteria, increased specifically in the suppressive peats, although no single bacterial group was associated with disease suppression. Fungal DGGE profiles varied little over the course of the bioassay; however, two bands associated specifically with suppressive samples were detected. Sequences from these bands corresponded to Basidiomycete yeast genera. Although the DGGE profiles were similar, fungal sequence diversity also increased during the bioassay. Sequences highly similar to those of Cryptococcus increased in relative abundance during the bioassay, particularly in the suppressive samples. This study highlights the importance of using complementary approaches to molecular profiling of complex populations and provides the first report that basidiomycetous yeasts may be associated with the suppression of Pythium-induced diseases in peats.

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Mycostop - A Novel Biofungicide Based on Streptomyces Bacteria

Cited by 44 publications

References 2 publications

Microbial and biochemical basis of a Fusarium wilt-suppressive soil

Microbial and biochemical basis of a Fusarium wilt-suppressive soil

Evidences of biological control capacities of Streptomyces spp. against Sclerotium rolfsii responsible for damping-off disease in sugar beet (Beta vulgaris L.)

Differences in Microbial Activity and Microbial Populations of Peat Associated with Suppression of Damping-Off Disease Caused by Pythium sylvaticum

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