Mycosis fungoides: The great imitator

Zackheim, Herschel S.; McCalmont, Timothy H.

doi:10.1067/mjd.2002.124696

Cited by 135 publications

(104 citation statements)

References 38 publications

(36 reference statements)

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“…If this is indeed the case, one may speculate that our patient with evolution of SPP into MF might have had additional underlying genetic disturbances or received additional promotional stimuli leading to the survival of a T-cell clone and its progression. Those workers who strictly separate MF and SPP may still entertain another hypothesis in our case, namely that our patient had MF from the very beginning and MF, being a great clinical masquerader, [22][23][24] simulated SPP by being composed of small elongated patches.…”

Section: Discussionmentioning

confidence: 67%

A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: Report of a case and comparative retrospective study of 27 cases of “nonprogressive” small plaque parapsoriasis

Белоусова

Vaněček

Самцов

et al. 2008

Journal of the American Academy of Dermatology

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Section: Discussionmentioning

confidence: 67%

A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: Report of a case and comparative retrospective study of 27 cases of “nonprogressive” small plaque parapsoriasis

Белоусова

Vaněček

Самцов

et al. 2008

Journal of the American Academy of Dermatology

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“…Limitations of the investigation were the short follow-up time (median, 4-6 years) and the lack of evaluation of the effect of latency. Although evidence is indeed accumulating that psoriasis is associated with risk of cutaneous T-cell lymphomas in particular, possibly driving the association with increased risk of lymphoma overall in some studies, potential inflation of risk due to misclassification cannot be disregarded, as cutaneous T-cell lymphomas may initially mimic benign skin disorders, such as psoriasis (104). For other spondylarthropathies, data are scarce, with the exception of ankylosing spondylitis.…”

Section: Autoimmune/inflammatory Conditions Linked To Lymphomamentioning

confidence: 99%

Malignant Lymphomas in Autoimmunity and Inflammation: A Review of Risks, Risk Factors, and Lymphoma Characteristics

Smedby

Baecklund

Askling

2006

Cancer Epidemiology, Biomarkers &Amp; Prevention

218

146

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Certain autoimmune and chronic inflammatory conditions, such as Sjögren's syndrome and rheumatoid arthritis (RA), have consistently been associated with an increased risk of malignant lymphomas, but it is unclear whether elevated lymphoma risk is a phenomenon that accompanies inflammatory conditions in general. Likewise, it is debated whether the increased risk identified in association with some disorders pertains equally to all individuals or whether it varies among groups of patients with different phenotypic or treatment-related characteristics. It is similarly unclear to what extent the increased lymphoma occurrence is mediated through specific lymphoma subtypes. This update reviews the many findings on risks, risk levels, and lymphoma characteristics that have been presented recently in relation to a broad range of chronic inflammatory, including autoimmune, conditions. Recent results clearly indicate an association between severity of chronic inflammation and lymphoma risk in RA and Sjögren's syndrome. Thus, the average risk of lymphoma in RA may be composed of a markedly increased risk in those with most severe disease and little or no increase in those with mild or moderate disease. The roles of immunosuppressive therapy and EBV infection seem to be limited. Furthermore, RA, Sjögren's syndrome, systemic lupus erythematosus, and possibly celiac disease may share an association with risk of diffuse large B-cell lymphoma, in addition to well-established links of Sjögren's syndrome with risk of mucosa-associated lymphoid tissue lymphoma and of celiac disease with risk of small intestinal lymphoma. However, there is also obvious heterogeneity in risk and risk mediators among different inflammatory diseases. (Cancer Epidemiol Biomarkers Prev 2006;15(11):2069–77)

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“…In the promyelocytic phase skin lesions are often misdiagnosed as psoriasis and non specific dermatitis due its resemblance to these conditions. The rate of misdiagnosis is very common at this stage [12][13][14]. Another uncommon feature is the mottled skin pigmentation known as poikiloderma [15].…”

Section: Discussionmentioning

confidence: 99%

Mycosis Fungoides Presentation in Emergency

Shujaa¹,

Suriya²

2011

TOEMJ

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Abstract:We present the case of a young lady who presented to the department of emergency medicine (DEM) for evaluation of painful breast swelling and skin indurations involving 90% of the body surface. She stayed long in the DEM for 3 days and managed for breast abscess she was consulted to dermatology for evaluation of skin lesions and preliminary diagnosed as rare skin T cell lymphoma. Final diagnosis based on clinical and histopathological was Mycosis Fungoids (MF).This case reveals that prompt referral from the DEM to the concerned speciality even for the rare type of diseases like MF can facilitate diagnosis and management and overall positive impact on disease outlook. Our patient was finally admitted under oncology unit and managed appropriately.

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Mycosis fungoides: The great imitator

Cited by 135 publications

References 38 publications

A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: Report of a case and comparative retrospective study of 27 cases of “nonprogressive” small plaque parapsoriasis

A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: Report of a case and comparative retrospective study of 27 cases of “nonprogressive” small plaque parapsoriasis

Malignant Lymphomas in Autoimmunity and Inflammation: A Review of Risks, Risk Factors, and Lymphoma Characteristics

Mycosis Fungoides Presentation in Emergency

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