Mycosis fungoides presenting as areas of hypopigmentation

Zackheim, Herschel S.; Epstein, Ervin; Grekin, David A.; McNutt, N. Scott

doi:10.1016/s0190-9622(82)70026-x

Cited by 66 publications

(43 citation statements)

References 4 publications

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“…The first descriptions of MF in skin of color were the reports of hypopigmented MF. [19][20][21] These first reports considered the hypopigmented form of MF to be a rare form of a rare disease. However, the epidemiology of the disease has confirmed a considerable presence of MF in patients with skin of color, 22 and the hypopigmented form of MF is a common finding within this population.…”

Section: Mycosis Fungoides In Skin Of Colormentioning

confidence: 99%

Cutaneous T-cell lymphoma in skin of color

Hinds

Heald

2009

Journal of the American Academy of Dermatology

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Section: Mycosis Fungoides In Skin Of Colormentioning

confidence: 99%

Cutaneous T-cell lymphoma in skin of color

Hinds

Heald

2009

Journal of the American Academy of Dermatology

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“…The treatment of hypopigmented MF is not very different from that of typical MF; PUVA therapy appears to induce relatively rapid and complete remissions in the majority of cases and may be indicated as the firstline therapy (3,4,(6)(7)(8). PUVA therapy has been used for the treatment of MF since 1974, and many studies have documented long-term disease-free remissions (14).…”

Section: Hypopigmentation Is Unusual In Mfmentioning

confidence: 99%

A Case of Hypopigmented Mycosis Fungoides

Choe

Park

Cho

2000

The Journal of Dermatology

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“…So approximately 10% of cases of MF initially present with cutaneous tumors, the emblem form of MF.6 Other less common presen¬ tations of MF include bullous lesions7 and hypopigmented patches or plaques, especially in darkly pigmented patients. 8 Mycosis fungoides has pre¬ sented as a laryngeal tumor with subsequent cutane¬ ous involvement,6 and can be associated with dystrophic xanthomas,9 alopecia mucinosa,10 and sarcoidosis. "…”

Section: Discussionmentioning

confidence: 99%

Tumors on a Leg

McCadden¹,

Warren²

1987

Arch Dermatol

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A 64-year-old man presented with a two-year history of a slowly enlarging nontender pruritic mass on his left thigh. Two years prior to evaluation he had noticed two small scaling psoriasiform patches on his inner left thigh, each approximately one half inch in diameter. Treatment with topical steroid therapy for psoriasis had no effect on these lesions, whereas other psoriatic lesions on the left middle aspect of his abdomen resolved with therapy. No biopsy specimen was taken from these lesions. Over the following year the two left thigh patches expanded and coalesced, Figure 1.Figure 2.Figure 3.Figure 4.forming an elevated ringlike tumor. This tumor quadrupled in size during the next year. The patient denied any pain or weight loss. He noted a small psoriasiform lesion on his left calf at the time of admission.Physical examination revealed an annular, fungating, violaceous, weeping tumor with several ulcerations, approximately 16 X 25 cm, on the left medial and posterior aspects of the thigh (Fig 1). A second tumor of identical appear¬ ance, approximately 4.5 X 7 cm, was on the medial aspect of the left popliteal fossa. Enlarged inguinal lymph nodes were palpated bilaterally. Bone scan, left hip and left leg roentgenograms, and computed tomographic (CT) scan of the left leg revealed no muscle or bone involvement by tumor. Chest roentgenogram and CT scan of the abdomen were normal, as were the results of the following studies: complete blood cell count, serum SMA-18 chemistry analy¬ sis, quantitative immunoglobulin studies, urinalysis, bone marrow biopsy, and Sézary cell preparation. A left inguinal node biopsy specimen showed dermatopathic lymphadeni¬ tis with marked plasmacytosis. Immunologie typing and immunoperoxidase studies of a skin biopsy specimen from the larger tumor demonstrated a polytypic population of lymphocytes, predominantly T helper cells. The tumor biopsy specimen is shown in Figs 2 through 4.

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Mycosis fungoides presenting as areas of hypopigmentation

Cited by 66 publications

References 4 publications

Cutaneous T-cell lymphoma in skin of color

Cutaneous T-cell lymphoma in skin of color

A Case of Hypopigmented Mycosis Fungoides

Tumors on a Leg

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