Mycoplasma Pneumoniae with Atypical Stevens-Johnson Syndrome: A Diagnostic Challenge

Yachoui, Ralph; Kolasinski, Sharon L.; Feinstein, Daniel

doi:10.1155/2013/457161

Cited by 13 publications

(12 citation statements)

References 8 publications

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“…Erythema multiforme major sometimes presents exclusively with mucosal involvement and is termed atypical erythema multiforme major or Fuchs' syndrome, because this German author first reported the condition as ‘herpes oris conjunctivae' approximately 150 years ago [98]. Our review disclosed 37 patients affected with Mycoplasma respiratory infection and oral mucositis [5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35]. In addition, ocular involvement was noted in 36, genital in 26 (22 male and 4 female subjects) and anal in 3 cases.…”

Section: Resultsmentioning

confidence: 99%

“…Using the described strategy, 94 reports were retained for the final analysis [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92,93,94,95,96,97]: 1 in German [23], 1 in Italian […”

Section: Data Assessmentmentioning

confidence: 99%

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Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature

et al. 2015

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Background: Maculopapular or urticarial eruptions and erythema multiforme sometimes occur in patients affected with Mycoplasma pneumoniae respiratory infections. Further eruptions have also been reported. Objective: To review the literature addressing M. pneumoniae respiratory infection and rather unusual eruptions. Methods: Computer-based search in the US National Library of Medicine database as well as in the search engine Google. Results: We found a possible relationship between M. pneumoniae infection and Fuchs' syndrome (n = 37), varicella-like eruptions (n = 8), Henoch-Schönlein syndrome and further leukocytoclastic vasculitides (n = 21) and erythema nodosum (n = 11). A temporal relationship was also observed with 2 cases of Gianotti-Crosti syndrome. Finally, there exists reasonable evidence that pityriasis rosea Gibert and pityriasis lichenoides et varioliformis acuta Mucha-Habermann are not associated with Mycoplasma infections. Conclusion: This review implies that M. pneumoniae may cause, in addition to erythematous maculopapular (or urticarial) eruptions and erythema multiforme, Fuchs' syndrome and varicella-like eruptions. Furthermore, there is an intriguing link with leukocytoclastic vasculitides or erythema nodosum that deserves further investigation.

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Section: Resultsmentioning

confidence: 99%

Section: Data Assessmentmentioning

confidence: 99%

Unusual Eruptions Associated with Mycoplasma pneumoniae Respiratory Infections: Review of the Literature

et al. 2015

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“…4,33 The most commonly identified cause of SJS in children is infection and drug sensitivity for adults. 28,10,34,35 Viral agents associated with SJS include coxsackie virus, HSV, AIDS, influenza, hepatitis, mumps, and Epstein-Barr. Associated bacterial agents include group A beta-hemolytic streptococci, diphtheria, brucellosis, lymphogranuloma venereum, mycobacteria, MP, rickettsia, tularemia, and typhoid.…”

Section: 2930mentioning

confidence: 99%

Stevens-Johnson Syndrome without Skin Lesions: A Rare and Clinically Challenging Disease in the Urgent Setting

Anders¹,

Taylor²,

Kravchuk³

et al. 2015

Emerg Med Open J

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Stevens-Johnson syndrome, toxic epidermal necrolysis, and erythema multiforme are life threatening diseases causing mucocutaneous eruptions and can be difficult to manage medically. When oral tissues are involved, airway management can be of critical importance. Fluid and electrolyte imbalance are common and protocols to prevent secondary infection are initiated. All three conditions are rapidly evolving. Stevens-Johnson syndrome is more commonly associated with Mycoplasma pneumoniae in the pediatric population and drug hypersensitivity in adults, whereas erythema multiforme is mostly associated with herpes simplex virus in the adult population. These diseases are T-cell-mediated immune reactions, thought to represent a spectrum of the same disease. Clinical and immunohistochemical techniques are capable of differentiating Stevens-Johnson syndrome from erythema multiforme and provide insight into the possible underlying pathology creating the disease. Rare cases of Stevens-Johnson syndrome without skin manifestations have been associated with Mycoplasma pneumoniae and predominantly occur in males. In-hospital management is recommended to provide airway support, maintain fluid intake, electrolyte balance, obtain multi-speciality consultation, and to perform diagnostic testing. We describe a case of a 14 year old male with atypical Stevens-Johnson syndrome and a review of the literature.

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“…Mycoplasma infection has been associated with several skin manifestations, including erythema multiforme, macular and vesicular exanthems, urticaria, erythema nodosum, and Stevens-Johnson syndrome. 28 Dermatologic findings are uncommon in legionella pneumonia.…”

Section: Differential Diagnosis Considerations Mycoplasma Pneumoniaementioning

confidence: 99%

Severe Pneumonia Caused by Legionella pneumophila

Chahin

Opal

2017

Infectious Disease Clinics of North America

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Severe legionella pneumonia poses a diagnostic challenge and requires early intervention. Legionnaire's disease can have several presenting signs, symptoms, and laboratory abnormalities that suggest that Legionella pneumophila is the pathogen, but none of these are sufficient to distinguish L pneumophila pneumonia from other respiratory pathogens. L pneumophila is primarily an intracellular pathogen and needs treatment with antibiotics that efficiently enter the intracellular space.

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Mycoplasma Pneumoniae with Atypical Stevens-Johnson Syndrome: A Diagnostic Challenge

Cited by 13 publications

References 8 publications

Unusual Eruptions Associated with <b><i>Mycoplasma pneumoniae</i></b> Respiratory Infections: Review of the Literature

Unusual Eruptions Associated with <b><i>Mycoplasma pneumoniae</i></b> Respiratory Infections: Review of the Literature

Stevens-Johnson Syndrome without Skin Lesions: A Rare and Clinically Challenging Disease in the Urgent Setting

Severe Pneumonia Caused by Legionella pneumophila

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