Mycoplasma pneumoniae--Associated Cerebral Infarction in a Child

Abstract

The central nervous system's involvement is the most common reported extra-pulmonary manifestations of Mycoplasma pneumoniae infection, and stroke was one of the most special situations. We presented a 4-year-old child who presented with acute stroke on the third day of the onset of Mycoplasma respiratory tract infection. Brain magnetic resonance angiography demonstrated that occlusion of bilateral internal carotid arteries and vertebral arteries above the level of the first cervical vertebrate which is not been reported previously.

Lactate Dehydrogenase as a Biomarker for Prediction of RefractoryMycoplasma pneumoniaePneumonia in Children

“…Thus, those with unrecoverable damage due to refractory M. pneumoniae pneumonia cannot rehabilitate completely. [25][26][27][28] Although there is no case-control study on the benefit of steroids in refractory M. pneumoniae pneumonia, it is believed that early steroid therapy might prevent disease progression and reduce disease morbidity without adverse reactions. 29,30 However, it is impossible to initiate steroids early for all M. pneumoniae infections because most of them are self-limited, and there is no evidence to support the use of systemic steroids in community-acquired pneumonia due to other pathogens.…”

Mycoplasma pneumoniae as an Under- Recognized Agent of Vasculitic Disorders

“…Stroke can occur in children [Fu et al, 1998;Lee et al, 2009;Leonardi et al, 2005;Ovetchkine et al, 2002;Parker et al, 1981;Tanir et al, 2006;Visudhiphan et al, 1992] as well as in adults [Mulder & Spierings, 1987;Padovan et al, 2001;Senda et al, 2010;Snowden et al, 1990;Sočan et al, 2001;Sotgiu et al, 2003]. The middle cerebral arteries are most often affected [Fu et al, 1998;Leonardi et al, 2005;Mulder & Spierings, 1987;Parker et al, 1981;Senda et al, 2010;Sotgiu et al, 2003], though the internal carotid arteries are affected in a few cases Tanir et al, 2006;Visudhiphan et al, 1992].…”

Paradoxical Brain Embolism Induced by Mycoplasma pneumoniae Infection with Deep Venous Thrombus

“…Stroke related to M. pneumoniae infection has been reported in several cases (3)(4)(5)(6)(7)(8)(9), mainly in children (3)(4)(5)8). These reports proposed that the association is due to direct damage of the central nervous system (3,6), or other mechanisms such as vasculitis resulting from post-infectious immunological disorders (4).…”

“…These reports proposed that the association is due to direct damage of the central nervous system (3,6), or other mechanisms such as vasculitis resulting from post-infectious immunological disorders (4). These cases all reported normal coagulation values, although it is uncertain whether the timing of the coagulation tests was appropriate for detecting abnormal values.…”