“…On the other hand, phototherapy as anti-psoriatic therapy is contraindicated because it could exacerbate pemphigoid. Therefore, in the cases of coexistent pemphigoid and psoriasis several different therapeutical schemes encompassing methotrexate (10,14,15), dapson (31), azathioprine (26,27,32), cyclosporine (33,34), erythromycin with etretinate (35), acitretin (36), cyclophosphamide (11) and mycophenolate mofetil (37) have been proposed. We have demonstrated herein that therapy with metotrexate can be an effective therapeutical approach.…”