Mycobacterium vaccae Lysate Induces Anti-Allergic Immune Response In Vitro

Стрыгин, А. В.; Nesmiyanov, Pavel P.; Петров, В. И.; Tolkachev, B. E.; Морковин, Е. И.; Gutov, M V; Стрыгина, А О

doi:10.1007/s10517-020-05039-6

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…In support also of M. vaccae NCTC 11659-related strains affecting DC function, a study by Strygin and colleagues [ 264 ] found effects of both heat-killed and sonicated M. vaccae ATCC 15483 T (DSM 43292 T ) on DC function in co-cultures of DCs and CD4 + T cells from both human and murine sources. In their study, M. vaccae ATCC 15483 T was cultured in Middelbrook 7H9 medium, 10 10 cells/mL were diluted in PBS, and either sonicated on ice or autoclaved for 15 min at 120 °C.…”

Section: History Of Mycobacterium Vaccae Nctc 11659 Researchmentioning

confidence: 99%

Rapidly Growing Mycobacterium Species: The Long and Winding Road from Tuberculosis Vaccines to Potent Stress-Resilience Agents

Amoroso

Langgartner

Lowry

et al. 2021

IJMS

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Inflammatory diseases and stressor-related psychiatric disorders, for which inflammation is a risk factor, are increasing in modern Western societies. Recent studies suggest that immunoregulatory approaches are a promising tool in reducing the risk of suffering from such disorders. Specifically, the environmental saprophyte Mycobacterium vaccae National Collection of Type Cultures (NCTC) 11659 has recently gained attention for the prevention and treatment of stress-related psychiatric disorders. However, effective use requires a sophisticated understanding of the effects of M. vaccae NCTC 11659 and related rapidly growing mycobacteria (RGMs) on microbiome–gut–immune–brain interactions. This historical narrative review is intended as a first step in exploring these mechanisms and provides an overview of preclinical and clinical studies on M. vaccae NCTC 11659 and related RGMs. The overall objective of this review article is to increase the comprehension of, and interest in, the mechanisms through which M. vaccae NCTC 11659 and related RGMs promote stress resilience, with the intention of fostering novel clinical strategies for the prevention and treatment of stressor-related disorders.

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Section: History Of Mycobacterium Vaccae Nctc 11659 Researchmentioning

confidence: 99%

Rapidly Growing Mycobacterium Species: The Long and Winding Road from Tuberculosis Vaccines to Potent Stress-Resilience Agents

Amoroso

Langgartner

Lowry

et al. 2021

IJMS

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“…But, if so, it is certainly not providing the best scientific ideas that century had to offer [3]. [ [34][35][36][37][38][39] Closed Gyms Exercise benefits the microbiome and microbiome-related metabolism Sedentary lifestyle risks for microbiome composition and microimmunosome function.…”

Section: Public Health Mandates That Ignore Fundamental Superorganism Biology and The Microbiome Revolutionmentioning

confidence: 99%

The Microbiological Basis of Human Superorganism Freedom

Dietert

2021

AJBSR

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accomplishments (which included bringing genetics to much of Latin America [2], Dobzhansky formulated paradigm-shifting science through what became known as the "balance hypothesis."This hypothesis stresses that lots of genetic variation within populations is a wonderful thing as it provides equal opportunity for success. It is the foundation of how earth organisms, especially humans, naturally operate. These views both reflected his research findings and helped to mold his world view.

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