Mycobacterium bovis at the animal–human interface: A problem, or not?

Michel, Anita Luise; Müller, Borna; Helden, Paul D. van

doi:10.1016/j.vetmic.2009.08.029

Cited by 278 publications

(277 citation statements)

References 89 publications

(93 reference statements)

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“…Although the impact of bTB may be significant in Africa, affecting the economy, the ecosystem and human health [28], wildlife TB is currently not considered a priority for most African countries. M. bovis has been isolated from a wide range of wild free-ranging mammals, including maintenance hosts in natural conditions, which will considerably complicate future bTB control programmes [101], and possibly compromise the chances of eradication in sub-Saharan African countries.…”

Section: Conclusion Knowledge Gaps and The Way Forwardmentioning

confidence: 99%

“…However, this technical limitation will probably remain a major challenge because the veterinary bTB diagnostic market is very small, and virtually non-existent for (African) wildlife [105]. In addition, new developments in the field are often not suitable for developing countries, either because they require sophisticated laboratory infrastructure and/or well-trained personnel [28]. In the long term, the development of effective vaccines could significantly contribute to protecting targeted wildlife populations and/or maintaining bTB prevalence below a threshold that would reduce the risk of spillback to livestock.…”

Section: Conclusion Knowledge Gaps and The Way Forwardmentioning

confidence: 99%

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A review of bovine tuberculosis at the wildlife–livestock–human interface in sub-Saharan Africa

et al. 2013

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SUMMARYInfection of wild animals by bovine tuberculosis (bTB) is raising concern worldwide. This article reviews the current epidemiological situation, risk of emergence and control options at the wildlife-livestock-human interface in sub-Saharan Africa. In livestock, bTB has been confirmed in the majority of countries from all parts of the continent. Wildlife infection is confirmed in seven countries from southern and eastern Africa, apparently spreading in the southern Africa region. Mycobacterium bovis has been isolated from 17 wild mammal species, although only four are suspected to play a role as maintenance host. Zoonotic risks are a concern, but no direct spillover from wildlife to humans has been documented, and no case of bTB spillback from wildlife to livestock has been confirmed. In this paper we assess the main risk factors of bTB spillover at the wildlife-livestock-human interface and suggest several research themes which could improve the control of the disease in the African context.

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Section: Conclusion Knowledge Gaps and The Way Forwardmentioning

confidence: 99%

Section: Conclusion Knowledge Gaps and The Way Forwardmentioning

confidence: 99%

A review of bovine tuberculosis at the wildlife–livestock–human interface in sub-Saharan Africa

et al. 2013

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“…Bovine tuberculosis in water buffalo has been described worldwide (MICHEL et al, 2010). Although it has also been reported in Brazil (PORTUGAL et al, 1971;MOTA et al, 2002;RIBEIRO et al, 2003), the data on its prevalence and distribution in different areas are very scarce, particularly in Brazilian Amazonia.…”

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confidence: 99%

“…Although almost all herds are raised using extensive production systems, during the rainy season when most of the area is flooded, animals are confined to very small feeding areas or are even raised on ships. Such high density can increase the likelihood of the spread of the disease, since close contact with infected animals is recognized as one of the major risk factors for the transmission of bovine tuberculosis (HEINEMANN et al, 2008;MICHEL et al, 2010).…”

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Tuberculosis in water buffalo (Bubalus bubalis) in the Baixo Araguari Region, Amapá, Brazil

et al. 2016

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Water buffalo are of great economic importance in Brazilian Amazonia, which has the largest herd in Brazil. Bovine tuberculosis caused by Mycobacterium bovis is a zoonotic disease that results in severe losses to water buffalo production. Although the disease has already been described in the country, data on the occurrence and distribution of bovine tuberculosis in water buffalo in Brazil is very scarce. The aim of this study was to determine the frequency of bovine tuberculosis in water buffalo in the Baixo Araguari River region of Amapá, Brazil. Thirty herds, randomly selected from the 41 herds of water buffalo in the region, were sampled. From those herds, 212 randomly selected water buffalo were subjected to the comparative tuberculin skin test. The proportion of Baixo Araguari River region herds that were positive for bovine tuberculosis was 50.0% (95% CI 31.3% to 68.7%) and the proportion of animals that were positive was estimated to be 14.8% (95% CI 7.8% to 21.9%). Our results show that bovine tuberculosis is spread widely among water buffalo in the Baixo Araguari River region, which suggests that measures to control the disease should be undertaken in the region. Key words: Brazilian Amazon. Comparative tuberculin skin test. Epidemiology. Mycobacterium bovis. ResumoA criação de búfalos é de grande importância econômica na Região Amazônica, que abriga o maior rebanho do Brasil. A tuberculose causada pelo Mycobacterium bovis é uma zoonose que leva a perdas severas na criação de búfalos. Apesar de já ter sido descrita no país, dados sobre a ocorrência e distribuição da

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Tuberculosis in animals in South Africa

Kriek

2014

Zoonotic Tuberculosis

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Mycobacterium bovis at the animal–human interface: A problem, or not?

Cited by 278 publications

References 89 publications

A review of bovine tuberculosis at the wildlife–livestock–human interface in sub-Saharan Africa

A review of bovine tuberculosis at the wildlife–livestock–human interface in sub-Saharan Africa

Tuberculosis in water buffalo (Bubalus bubalis) in the Baixo Araguari Region, Amapá, Brazil

Tuberculosis in animals in South Africa

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