Mycobacterium africanum Presenting as a Brain Mass

Bhanot, Nitin; Badem, Olga; Mathew, Liby; Haran, Mehandi

doi:10.1097/ipc.0b013e3181637a0f

Cited by 4 publications

(5 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Case reports describe extra-pulmonary TB caused by M. africanum as disseminated disease [41], cutaneous disease [42], orchiepididymitis [40], prostatitis [43], pleural disease [44], bone disease [45], brain mass [46], and proctitis [47]. However, in most cases, TB patients carrying M. africanum were immigrants from West Africa.…”

Section: Resultsmentioning

confidence: 99%

“…M. africanum has sporadically been identified in areas outside of the West African region, including Germany [9] , [35] , [36] , England [37] , California [38] , France [39] , and Spain [40] , both from pulmonary and extra-pulmonary sources. Case reports describe extra-pulmonary TB caused by M. africanum as disseminated disease [41] , cutaneous disease [42] , orchiepididymitis [40] , prostatitis [43] , pleural disease [44] , bone disease [45] , brain mass [46] , and proctitis [47] . However, in most cases, TB patients carrying M. africanum were immigrants from West Africa.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

2010

View full text Add to dashboard Cite

Mycobacterium africanum consists of two phylogenetically distinct lineages within the Mycobacterium tuberculosis complex, known as M. africanum West African 1 and M. africanum West African 2. These lineages are restricted to West Africa, where they cause up to half of human pulmonary tuberculosis. In this review we discuss the definition of M. africanum, describe the prevalence and restricted geographical distribution of M. africanum West African 1 and 2, review the occurrence of M. africanum in animals, and summarize the phenotypic differences described thus far between M. africanum and M. tuberculosis sensu stricto.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

2010

View full text Add to dashboard Cite

show abstract

“…Searching the literature, we found just three cases of CT 6,7 , none of them amongst children. This agent is rarely found in Europe [7][8][9] , but is common in West and Central Africa, including Guinea-Bissau, from where our patient was from. In these areas Mycobacterium africanum is responsible for 50-60% of all cases of pulmonary TB 5 .…”

Section: Discussionmentioning

confidence: 72%

“…As noted previously, infection caused by Mycobacterium africanum is indistinguishable from other mycobacteria 9 ; however, is recommendable to identify the species, not only due to epidemiological matters, to detect and control outbreaks 11 , but also because Mycobacterium bovis is resistant to pyrazinamid 9 , which has obvious implications in treatment. In industrialized countries, where CT is extremely rare, is important to remember this entity, which can be found associated with systemic forms or be the only manifestation of the mycobacterial infection.…”

Section: Discussionmentioning

confidence: 98%

Infeção Cutânea E Pulmonar Por Mycobacterium Africanum

Francisco

Cunha

Vieira

et al. 2013

SPDV

View full text Add to dashboard Cite

A tuberculose cutânea é uma doença incomum, constituindo 1,5% de todas as formas de tuberculose. Na doença pulmonar e cutânea, as infeções causadas por Mycobacterium africanum e Mycobacterium tuberculosis podem ser clinicamente indistinguíveis. Um rapaz de 6 anos da Guiné-Bissau foi hospitalizado devido a uma úlcera pré-auricular direita com evolução de dois anos e linfadenopatia regional. O teste tuberculínico foi positivo e a radiografia de tórax revelou um nódulo hipotransparente no lobo pulmonar direito, com características sólidas na TAC. As biópsias da úlcera e da linfadenopatia revelaram infiltrado linfocítico com reação granulomatosa; o exame cultural e a PCR confirmaram infeção por Mycobacterium africanum. Foi realizado tratamento antibacilar durante 6 meses, com redução significativa da lesão. Nos países desenvolvidos é importante relembrar as várias formas de tuberculose cutânea, que se pode apresentar isoladamente ou em associação com outras formas de infeção. Nos doentes provenientes de áreas endémicas, um teste tuberculínico positivo deve levantar a suspeita desta entidade. PALAVRAS-CHAVE – Tuberculose cutânea; Tuberculose pulmonar; Mycobacterium africanum; Criança.

show abstract

“…1 The pathogenesis of stroke is complex and the etiology is multifactorial but hyperlipidemia, metabolic syndrome, and atherosclerosis are a few important risk factors for both hemorrhagic and ischemic stroke. 1,2…”

Section: Introductionmentioning

confidence: 99%

Association of atherogenic cardiac index and markers of oxidative stress in non-diabetic dyslipidemia stroke patients in a tertiary care hospital in Eastern India

Anannya Ghosh,

Apratim Chatterjee,

Sanchayan Sinha

2024

Asian J Med Sci

View full text Add to dashboard Cite

Background: Stroke is a clinical syndrome consisting of rapidly developing clinical signs of focal or global disturbance of cerebral function. Antioxidants are exogenous or endogenous compounds acting by scavenging reactive oxygen species or their precursors, inhibiting reactive oxygen species formation and binding metal ions needed for the catalysis of its generation. Atherogenic index, a predictor of atherosclerosis, increases in dyslipidemia also shows a positive association with oxidative stress. Aims and Objectives: Our objective was to compare the lipid profile, the markers of lipid peroxidation (malonaldehyde and paraoxonase [PON]), and atherogenic index in non-diabetic stroke patients with healthy controls and to evaluate the correlation between the lipid parameters with markers of lipid peroxidation and atherogenic index in those patients. Materials and Methods: One hundred diagnosed stroke patients from the Neurology department were compared with 100 age-matched healthy controls. Estimation of lipid profile parameters was done by AutoAnalyzer using standardized kits. Estimation of serum malonaldehyde was done based on the principle of utilization of Thiobarbituric acid. Serum PON1 activity was estimated using paranitrophenyl acetate substrate. Results: Among the lipid profile parameters, high-density lipoprotein (HDL) was significantly lower (P<0.001) and low-density lipoprotein (LDL) was significantly higher among stroke patients. Serum malonaldehyde level was significantly increased and PON1 activity was significantly decreased in stroke patients in comparison to healthy individuals. A significant positive correlation between HDL and PON1 and a negative correlation between LDL and PON1 were found. Atherogenic index is negatively correlated with PON1. Conclusion: Low level of PON1 activity and an increased level of malonaldehyde were found in stroke patients indicating an imbalance between free radical generation and its scavenging action and also associated with more chance of atherosclerosis.

show abstract

Mycobacterium africanum Presenting as a Brain Mass

Cited by 4 publications

References 12 publications

Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

Mycobacterium africanum—Review of an Important Cause of Human Tuberculosis in West Africa

Infeção Cutânea E Pulmonar Por Mycobacterium Africanum

Association of atherogenic cardiac index and markers of oxidative stress in non-diabetic dyslipidemia stroke patients in a tertiary care hospital in Eastern India

Contact Info

Product

Resources

About