Mycobacterium abscessus Infection After Facial Injection With Autologous Fat

Abstract

We report a case of Mycobacterium abscessus infection in a 29-year-old woman after facial injection with autologous fat. Nineteen months previously, she received a facial surgery of autologous fat injection with the fat harvested from her inner thigh. On examination, she had multiple painful and fluctuant abscesses associated with local pyrexia in her bilateral temporal and lower orbital regions. A B ultrasound revealed multiple fat liquefaction in her bilateral temporal and lower orbital regions. The acid-fast bacilli culture and polymerase chain reaction sequencing confirmed M. abscessus infection. She was treated with moxifloxacin, clarithromycin, and ethambutol for 12 months, and finally the symptoms subsided. To avoid infection after fat graft, aseptic technique as well as standard operation of the fat harvest and process should be strictly enforced. In cases of persistent infection, or invalid cases treated with conventional antibiotic therapy, nontuberculous mycobacteria should be suspected, and a polymerase chain reaction sequencing as well as a drug sensitivity test should be carried out.

Subcutaneous infection caused by Mycobacterium abscessus following cosmetic injections of botulinum toxin: A case report

“…To meet the challenge of NTM diagnosis and management, we should learn more about it. In Table 1 , previous cases of mycobacterial infections caused by cosmetic performance are reviewed[ 2 - 4 , 6 - 14 ], the results of which are consistent with the previous studies[ 1 ]. It is common to be seen in female patients aged 25 to 45 years.…”

Subcutaneous infection caused by Mycobacterium abscessus following botulinum toxin injections: A case report and literature review

“…A total of 24 cases across 18 studies of cutaneous NTM infection after cosmetic injections reported from 2013 to 2023 were identified in the search. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21] The characteristics of the included studies are summarized in Table 1. The majority of the patients were female (23 out of 24 patients), with ages ranging from 28 to 56 years old.…”

“…A total of 24 cases across 18 studies of cutaneous NTM infection after cosmetic injections reported from 2013 to 2023 were identified in the search 4–21 …”

“…One of the most important reasons for the rapid increase in the inci- Clarithromycin 500 mg qd and levofloxacin 500 mg qd None 6 months Histopathologically confirmed [13] Clarithromycin 500 mg bid 2.5 m, ciprofloxacin 500 mg bid 3 m Surgical excision 4 months M. chelonae [14] Clarithromycin and moxifloxaci 12 m None 18 months M. abscessus [15] Moxifloxacin, clarithromycin, and ethambutol 12 m Debridement 14 months M. abscessus [16] Terbinafine 250 mg qd, clarithromycin 250 mg bid, and doxycycline 100 mg qd 3 m…”

Mycobacterium mageritense subcutaneous infection following cryopreserved facial fat injection: A report of 2 cases

“…Autologous fat injection is a cosmetic procedure performed to enhance the cosmetic appearance. 1 , 2 , 3 Infections with nontuberculous mycobacteria (NTM), such as Mycobacterium fortuitum , following cryopreserved fat injection have been reported. 1 Mycobacterium mageritense is a rapidly growing NTM, and to date, there have been only a few reported cases of skin and soft tissue infection with M mageritense .…”