Mycobacterial Cervical Lymphadenopathy

Lai, Kwan Kew; Stottmeier, K. D.; Sherman, I H; McCabe, William R.

doi:10.1001/jama.1984.03340340026019

Cited by 126 publications

(6 citation statements)

References 14 publications

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“…[ 4 ] dNTM infection can mimic soft tissue malignancy, lymphoma, and cancer metastasis. [ 8 – 11 ] In contrast to NTM infection of the head and neck region in children, [ 12 – 16 ] NTM-caused cervical lymphadenitis is rare in adults. [ 12 ] Most of the reported NTM infection with parotitis in adults have underlying immunodeficiency, such as HIV infection or rheumatic disease with steroid use.…”

Section: Discussionmentioning

confidence: 99%

“…[ 8 – 11 ] In contrast to NTM infection of the head and neck region in children, [ 12 – 16 ] NTM-caused cervical lymphadenitis is rare in adults. [ 12 ] Most of the reported NTM infection with parotitis in adults have underlying immunodeficiency, such as HIV infection or rheumatic disease with steroid use. [ 17 – 20 ] Here, we reported our unusual case of disseminated M abscessus infection that involved parotid glands with multiple lymphadenopathies in a person with an underlying relatively immunocompetent condition.…”

Section: Discussionmentioning

confidence: 99%

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Anti-interferon-γ autoantibody-associated disseminated Mycobacterium abscessus infection mimicking parotid cancer with multiple metastases

Chang

Chuang²

2017

Medicine

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Rationale:Among the nontuberculous mycobacteria, Mycobacterium abscessus is a common cause of skin, soft tissue, and bone infections. However, disseminated M. abscessus infection that mimics cancer metastasis with an underlying relatively immunocompetent condition has rarely been reported.Patient concerns:A nonsmoking 73-year-old man with an underlying relatively immunocompetent condition reported a 2-month history of a mass in the region of his right parotid gland that had been steadily increasing in size.Diagnoses:The head and neck computed tomography showed an avidly enhancing tumor with central necrosis in the right parotid region and lymphadenopathy bilaterally at neck levels II–V (<6 cm) with a necrotic core. The radiologist and otolaryngologist both suspected a diagnosis of right parotid gland cancer with metastasis.Interventions:The necrotic tissue was removed surgically, and Mycobacterium culture showed M. abscessus. We collected a blood sample and detected anti-interferon-γ autoantibody.Outcomes:After 6 months of anti-M. abscessus treatment, physical examination showed remission of the parotid tumor, and axillary and supraclavicular lymphadenopathy.Lessons:We report a case of disseminated M. abscessus infection, which involved parotid glands with multiple lymphadenopathies in a person with an underlying relatively immunocompetent condition. Possible underlying mechanisms such as anti-interferon-γ autoantibody-associated immunodeficiency should be considered in a patient with disseminated M. abscessus infection without a known immunocompromised condition.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Anti-interferon-γ autoantibody-associated disseminated Mycobacterium abscessus infection mimicking parotid cancer with multiple metastases

Chang

Chuang²

2017

Medicine

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“…Tuberculosis lymphadenitis is usually found in the supraclavicular area or the posterior triangle of the neck and is frequently the same site for metastasis from papillary thyroid carcinoma (7, 8). …”

Section: Discussionmentioning

confidence: 99%

Tuberculous Cervical Lymphadenitis Masquerding as Metastatis From Papillary Thyroid Carcinoma

Andrabi¹,

Bhat²,

Farhana³

et al. 2012

Int J Endocrinol Metab

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Clinically apparent cervical lymphadenopathy has been found at the initial presentation in 23 to 56 % of cases of papillary thyroid carcinoma. Here we report tuberculous lymphadenitis mimicking metastatic lymph nodes from papillary thyroid carcinoma and suggest that tuberculosis apart from metastasis in papillary thyroid carcinoma should also be considered in the etiology of enlarged lymph nodes in such patients, especially in those with risk factors for tuberculosis. Therefore, the importance of careful pre-operative evaluation of cervical lymph node metastasis cannot be overestimated, so that patients do not undergo unnecessary neck dissection for other benign conditions.

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Section: Saif Andrabi Sm Et Al Tubercular Lymphadenitis Masquerding mentioning

confidence: 99%

Tuberculous Cervical Lymphadenitis Masquerding as Metastatis From Papillary Thyroid Carcinoma

Žofková

2012

Int J Endocrinol Metab

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Mycobacterial Cervical Lymphadenopathy

Cited by 126 publications

References 14 publications

Anti-interferon-γ autoantibody-associated disseminated Mycobacterium abscessus infection mimicking parotid cancer with multiple metastases

Anti-interferon-γ autoantibody-associated disseminated Mycobacterium abscessus infection mimicking parotid cancer with multiple metastases

Tuberculous Cervical Lymphadenitis Masquerding as Metastatis From Papillary Thyroid Carcinoma

Tuberculous Cervical Lymphadenitis Masquerding as Metastatis From Papillary Thyroid Carcinoma

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