Mycetoma caused by Microsporum canis in a patient with renal transplant: A case report and review of the literature

Abstract

Microsporum canis is a dermatophyte known to cause superficial skin infections. In immunocompromised patients, it can lead to invasive dermatophytosis. We present a case of biopsy-proven left knee mycetoma caused by M canis in a renal transplant patient. Identification of M canis was achieved via sequencing of the internal transcribed spacer regions. Treatment involved surgical debridement, oral posaconazole, and reduction in immunosuppression. In addition, we provide a review of current literature on invasive M canis infections.

Mycetoma by Actinomadura madurae in the central nervous system: Renal transplant receptor disease

“…This pathology has recently been classified into a neglected disease, commonly observed in poor, low‐income countries. 6 …”

“…However, the treatment of actinomycetoma in most cases is prolonged, with complications, often expensive or with adverse events. 6 …”

“…In vitro, the susceptibility of A. madurae to TMP/SMX is high, as is the efficacy in clinical practice. However, the treatment of actinomycetoma in most cases is prolonged, with complications, often expensive or with adverse events 6 …”

“…This pathology has recently been classified into a neglected disease, commonly observed in poor, low-income countries. 6 The patient is a rural community worker, 7 who lived in close contact with livestock, 8 in Jalisco, Mexico, an endemic region of Actinomadura madurae. 9 Male gender has been usually associated with mycetoma caused by Nocardia Brasiliensis.…”

“…However, the treatment of actinomycetoma in most cases is prolonged, with complications, often expensive or with adverse events. 6 Mycetoma caused by Actinomadura madurae is characterized by a continuous secretion, 1,10 suspected by the development of abscess. A bypass valve was needed to treat hydrocephaly.…”