Myasthenia Gravis Accompanied by Thymomas Not Related to Foamy Virus Genome in Belarusian’s Patients

Kuzmenok, O.; Dvoryanchikov, Gennady; Ponomareva, Ekaterina N.; Goncharov, Aleksey A.; Fomin, I.K.; Lee, Sho-Tone; Sanberg, Paul R.; Потапнев, М. П.

doi:10.1080/00207450701239442

Cited by 3 publications

(2 citation statements)

References 14 publications

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“…Two reports described detection of human foamy virus, a retrovirus, in patients with thymoma or myasthenia gravis (26,27), but subsequent larger studies did not confirm the findings (28,29). In 2002, Manca et al reported finding evidence for human T-cell lymphotropic virus type 1 infection in myasthenia gravis patients, some of whom had thymoma (30), but again these findings were not confirmed (28).…”

Section: Possible Risk Factors For Thymomamentioning

confidence: 99%

Epidemiology of Thymoma and Associated Malignancies

Engels

2010

Journal of Thoracic Oncology

464

350

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Thymoma is a rare malignancy of unknown etiology. Based on cancer registry data, the overall incidence of thymoma in the U.S. is 0.13 per 100,000 person-years. Thymoma is exceedingly uncommon in children and young adults, rises in incidence in middle age, and peaks in the seventh decade of life. For unknown reasons, thymoma incidence is especially high among Asians and Pacific Islanders in the U.S. While several studies based at single treatment centers have suggested that thymoma patients have a broadly increased risk for other malignancies, follow up data from U.S. cancer registries support a more limited spectrum of cancer risk. In particular, people with thymoma have a subsequently elevated risk for developing B-cell non-Hodgkin lymphoma, consistent with an effect of immune disturbance arising from the thymoma or its treatment. Based on limited data, thymoma patients may also have an elevated risk for developing soft tissue sarcomas. While these descriptive epidemiologic data may yield clues to the etiology of thymoma, large multi-center case-control studies will be required to formally evaluate environmental and genetic risk factors.

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Section: Possible Risk Factors For Thymomamentioning

confidence: 99%

Epidemiology of Thymoma and Associated Malignancies

Engels

2010

Journal of Thoracic Oncology

464

350

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“…Samples were screened for multiple pathogens as described in detail elsewhere, including: leptospira and anthrax [17], herpesviruses [18], filoviruses [19], paramyxoviruses [20], coronaviruses [21], flaviviruses [22], orthopoxviruses [23] and simian retroviruses (SIV, STLV, SFV) [24][25][26][27][28][29]. All PCR-amplified bands approximately the expected size were confirmed by sequencing.…”

Section: Microbial Screeningmentioning

confidence: 99%

Zoonotic Viruses Associated with Illegally Imported Wildlife Products

et al. 2012

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The global trade in wildlife has historically contributed to the emergence and spread of infectious diseases. The United States is the world's largest importer of wildlife and wildlife products, yet minimal pathogen surveillance has precluded assessment of the health risks posed by this practice. This report details the findings of a pilot project to establish surveillance methodology for zoonotic agents in confiscated wildlife products. Initial findings from samples collected at several international airports identified parts originating from nonhuman primate (NHP) and rodent species, including baboon, chimpanzee, mangabey, guenon, green monkey, cane rat and rat. Pathogen screening identified retroviruses (simian foamy virus) and/or herpesviruses (cytomegalovirus and lymphocryptovirus) in the NHP samples. These results are the first demonstration that illegal bushmeat importation into the United States could act as a conduit for pathogen spread, and suggest that implementation of disease surveillance of the wildlife trade will help facilitate prevention of disease emergence.

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Myastenia and small doses of ionizing radiation: experience of successful use of rituximab for treatment of an irradiated with myasthenia gravis

Кравченко

Чумак

Loganovsky

et al. 2017

Probl Radiac Med Radiobiol

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Описано клінічний випадок застосування ритуксимабу для лікування постраждалого внаслідок аварії на Чорно бильській АЕС зі злоякісною резистентною формою міастенії у поєднанні з хронічною мікст інфекцією токсоп лазмами, вірусами Епштейна Барр, цитомегалії і простого герпесу. У динаміці дворічного спостереження пока зана клінічна ефективність моноклональних антитіл у вигляді стабілізації основних симптомів і зниження доз антихолінестеразної і глюкортикоїдної терапії. Позитивний ефект відмічався в найближчий і віддалений періоди. Враховуючи ефективність, безпечність і добру переносимість ритуксимабу, його доцільно рекоменду вати для лікування осіб, які зазнали впливу іонізуючої радіації і захворіли на міастенію, асоційовану з хронічною мікст інфекцією токсоплазмами, вірусами Епштейна Барр, цитомегалії і простого герпесу.

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Myasthenia Gravis Accompanied by Thymomas Not Related to Foamy Virus Genome in Belarusian’s Patients

Cited by 3 publications

References 14 publications

Epidemiology of Thymoma and Associated Malignancies

Epidemiology of Thymoma and Associated Malignancies

Zoonotic Viruses Associated with Illegally Imported Wildlife Products

Myastenia and small doses of ionizing radiation: experience of successful use of rituximab for treatment of an irradiated with myasthenia gravis

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