“…Researchers studying "cross-talk" between these two pathways have identified IPP as a likely candidate for exchange between the plastid and cytosol, however no plastidmembrane components capable of prenyl diphosphate transport have been identified (Lipko and Swiezewska, 2016). IP has also been highlighted as a potential "exchangeable" intermediate between the plastid and cytosol (Sun et al, 2016), and here, too, we see evidence of transport in E. coli. Extracellular IP was detected in strain 3Amk and the comparably "healthy" strain 3A,…”