MXene-Ti3C2/CuS nanocomposites: Enhanced peroxidase-like activity and sensitive colorimetric cholesterol detection

Li, Yapeng; Kang, Zewen; Kong, Lingyao; Shi, Huiting; Zhang, Yanzhou; Cui, Ma-Lin; Yang, Da‐Peng

doi:10.1016/j.msec.2019.110000

Cited by 94 publications

(45 citation statements)

References 58 publications

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“…(48) The results of detecting cholesterol in human serum in three tests under the same conditions proved that this MXene-based nanocomposite could be applied to practical clinical diagnosis. (48) Also, Wang et al designed an electrochemical DNA (E-DNA) biosensor based on DNA nanostructure-modified MXene (Ti 3 C 2 ) nanosheets to detect gliotoxin. (49) According to Wang et al, gliotoxin is one of the most toxic metabolites, resulting from the growth of Aspergillus fumigatus, and is harmful to the human body and linked to asthma.…”

Section: Cancer Biomarker Detectionmentioning

confidence: 75%

“…(10) Cholesterol is a kind of sterol found in the blood plasma of mammals, and an abnormal level of cholesterol increases the risk of cardiovascular diseases. (48) Li et al proposed a novel 2D MXene-Ti 3 C 2 /CuS nanocomposite with peroxidase-like activity using a simple hydrothermal approach. (48) The results of detecting cholesterol in human serum in three tests under the same conditions proved that this MXene-based nanocomposite could be applied to practical clinical diagnosis.…”

Section: Cancer Biomarker Detectionmentioning

confidence: 99%

“…(48) Li et al proposed a novel 2D MXene-Ti 3 C 2 /CuS nanocomposite with peroxidase-like activity using a simple hydrothermal approach. (48) The results of detecting cholesterol in human serum in three tests under the same conditions proved that this MXene-based nanocomposite could be applied to practical clinical diagnosis. (48) Also, Wang et al designed an electrochemical DNA (E-DNA) biosensor based on DNA nanostructure-modified MXene (Ti 3 C 2 ) nanosheets to detect gliotoxin.…”

Section: Cancer Biomarker Detectionmentioning

confidence: 99%

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MXene-based Sensors for Detecting Human Physiological Information

Yuan¹,

Zhang²,

Wu³

2020

Sensors and Materials

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Section: Cancer Biomarker Detectionmentioning

confidence: 75%

Section: Cancer Biomarker Detectionmentioning

confidence: 99%

Section: Cancer Biomarker Detectionmentioning

confidence: 99%

See 1 more Smart Citation

MXene-based Sensors for Detecting Human Physiological Information

Yuan¹,

Zhang²,

Wu³

2020

Sensors and Materials

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“…In addition to MXene-based fluorescent biosensors, colorimetric optical biosensors based on MXene nanocomposites have been studied extensively due to their simplicity, rapid usage, low cost, and sensitive detection by naked eyes, which make them suitable for point-of-care testing [78][79][80][81]. For development of colorimetric optical biosensors, the peroxidase-like properties of MXenes are utilized.…”

Section: Mxene-based Fluorescent/optical Biosensorsmentioning

confidence: 99%

Recent Advances in MXene Nanocomposite-Based Biosensors

et al. 2020

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The development of advanced biosensors with high sensitivity and selectivity is one of the most demanded concerns in the field of biosensors. To meet this requirement, up until now, numerous nanomaterials have been introduced to develop biosensors for achieving high sensitivity and selectivity. Among the latest nanomaterials attracting attention, MXene is one of the best materials for the development of biosensors because of its various superior properties. MXenes are two-dimensional inorganic compounds with few atomic layers that possess excellent characteristics including high conductivity and superior fluorescent, optical, and plasmonic properties. In this review, advanced biosensors developed on the basis of the MXene nanocomposite are discussed with the selective overview of recently reported studies. For this, introduction of the MXene including the definition, synthesis methods, and its properties are discussed. Next, MXene-based electrochemical biosensors and MXene-based fluorescent/optical biosensors are provided, which are developed on the basis of the exceptional properties of the MXene nanocomposite. This review will suggest the direction for use of the Mxene nanocomposite to develop advanced biosensors with high sensitivity and selectivity.

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“…Thus, cholesterol level estimation is extremely important in clinical diagnosis. The different approaches, including high-performance liquid chromatography [3][4][5][6], near-infrared (IR) spectra [7][8][9], and colorimetric assay [10][11][12], have been used for cholesterol level detection. However, the abovementioned approaches are expensive and time consuming and require large amounts of serum samples [13,14].…”

Section: Introductionmentioning

confidence: 99%

Cerium Oxide/Polypyrrole Nanocomposite as the Matrix for Cholesterol Biosensor

Anh

Thu²,

Dang

et al. 2021

Advances in Polymer Technology

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A nanocomposite comprising cerium oxide nanoparticles (CeO2 NPs) and polypyrrole (PPy) was fabricated onto a microelectrode for cholesterol sensing application. The cholesterol oxidase (ChOx) was immobilized on the CeO2 NPs/PPy/electrode by the physical adsorption route. The structure and morphology of the CeO2 NPs/PPy nanocomposite were characterized by X-ray diffraction, field emission scanning electron microscopy, and energy dispersive X-ray spectroscopy. Results showed that the ChOx/CeO2 NPs/PPy/electrode was linearly related with cholesterol in the range of 50 to 500 mg/dL. The sensitivity of ChOx/CeO2 NPs/PPy/electrode was 5.7 × 10 − 6 mA/mg⋅dL−1. The optimal parameters, including pH value and temperature, and selectivity, storage stability, and reproducibility of ChOx/CeO2 NPs/PPy/electrode were investigated.

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MXene-Ti3C2/CuS nanocomposites: Enhanced peroxidase-like activity and sensitive colorimetric cholesterol detection

Cited by 94 publications

References 58 publications

MXene-based Sensors for Detecting Human Physiological Information

MXene-based Sensors for Detecting Human Physiological Information

Recent Advances in MXene Nanocomposite-Based Biosensors

Cerium Oxide/Polypyrrole Nanocomposite as the Matrix for Cholesterol Biosensor

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