MXene nanoflakes decorating ZnO tetrapods for enhanced performance of skin-attachable stretchable enzymatic electrochemical glucose sensor

Myndrul, Valerii; Coy, Emerson; Babayevska, Nataliya; Zahorodna, Veronika; Balitskyi, Vitalii; Baginskiy, Ivan; Gogotsi, Oleksiy; Bechelany, Mikhael; Giardi, Maria Teresa; Iatsunskyi, Igor

doi:10.1016/j.bios.2022.114141

Cited by 105 publications

(61 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ZnO tetrapods (ZnO TPs) were fabricated by the environmentally friendly, catalystfree oxidative-metal-vapor-transport method. The method includes thermal evaporation of Zn powder at 1000 • C for 1 h in the air in a ceramic crucible, followed by ZnO nucleation and ZnO TPs growth [1]. Obtained ZnO TPs powder was white, indicating the formation of ZnO from metallic Zn in presence of atmospheric O 2 .…”

Section: Methodsmentioning

confidence: 99%

“…The functionalization of ZnO TPs with Nafion was performed in accordance with our previous study [1]. In brief, the prepared ZnO TPs (3 mg) sample was mixed with Nafion (1 mL of 2% EtOH solution).…”

Section: Methodsmentioning

confidence: 99%

“…For example, the Nafion micelle membr The glucose detection on ZnO TPs/chitosan and ZnO TPs/Nafion electrodes were measured by chronoamperometry measurements (Figure 5c,d). The chronoamperometry curves were taken in the cathodic mode (negative potentials), which makes it possible to eliminate interference caused by other species [1]. The stairs-like behavior of the chronoamperometry curves indicated the typical response of the GOx-treated electrodes to different concentrations of glucose that were sequentially added to the electrochemical cell.…”

Section: Comparison Of Chitosan and Nafion Semi-permeable Membranesmentioning

confidence: 99%

“…Real-time glucose detection is a hot topic at the moment, since continuous glucose monitoring can preserve more than 420 million people over the world from severe consequences caused by diabetes, no matter the type [1]. In addition, continuous noninvasive glucose detection (e.g., indirect detection in sweat, tears, or saliva) has the advantage over conventional glucometers that require blood sampling by painful and frequent fingerpricking [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

“…The functionalization strategy of different transducers (including ZnO) usually requires several consequent steps to be performed. At the initial step, ZnO is treated with various cross-linking agents (e.g., glutaraldehyde) [1,26], at the second-glucose oxidase (GOx) deposition [27], and at the final-deposition of a polymer layer [28][29][30]. The last one plays an essential role, as it simultaneously performs several important functions: (i) prevents of GOx from leaking out, (ii) permits charge transfer through it, and (iii) reduces interference by ionic substances [31].…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Effect of Electrode Modification with Chitosan and Nafion® on the Efficiency of Real-Time Enzyme Glucose Biosensors Based on ZnO Tetrapods

et al. 2022

Self Cite

View full text Add to dashboard Cite

Noninvasive, continuous glucose detection can provide some insights into daily fluctuations in blood glucose levels, which can help us balance diet, exercise, and medication. Since current commercially available glucose sensors can barely provide real-time glucose monitoring and usually imply different invasive sampling, there is an extraordinary need to develop new harmless methods for detecting glucose in non-invasive body fluids. Therefore, it is crucial to design (bio)sensors that can detect very low levels of glucose (down to tens of µM) normally found in sweat or tears. Apart from the selection of materials with high catalytic activity for glucose oxidation, it is also important to pay considerable attention to the electrode functionalization process, as it significantly contributes to the overall detection efficiency. In this study, the (ZnO tetrapods) ZnO TPs-based electrodes were functionalized with Nafion and chitosan polymers to compare their glucose detection efficiency. Cyclic voltammetry (CV) measurements have shown that chitosan-modified ZnO TPs require a lower applied potential for glucose oxidation, which may be due to the larger size of chitosan micelles (compared to Nafion micelles), and thus easier penetration of glucose through the chitosan membrane. However, despite this, both ZnO TPs modified with chitosan and Nafion membranes, provided quite similar glucose detection parameters (sensitivities, 7.5 µA mM−1 cm−1 and 19.2 µA mM−1 cm−1, and limits of detection, 24.4 µM and 22.2 µM, respectively). Our results show that both electrodes have a high potential for accurate real-time sweat/tears glucose detection.

show abstract

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Comparison Of Chitosan and Nafion Semi-permeable Membranesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effect of Electrode Modification with Chitosan and Nafion® on the Efficiency of Real-Time Enzyme Glucose Biosensors Based on ZnO Tetrapods

et al. 2022

Self Cite

View full text Add to dashboard Cite

show abstract

An Enzymatic Electrochemical Biosensing Interface Developed by The Laser‐Induced Graphene Electrode

Liu,

Zhao,

Yang

et al. 2023

Adv Materials Inter

View full text Add to dashboard Cite

Laser‐inducing provides a cost‐effective, easily‐manufacturable, and environment‐friendly approach to directly transfer carbon‐rich polymers into graphene materials, which attracts attention from various fields, such as sensors, electrocatalysts, micro‐supercapacitors, etc. Laser‐induced graphene (LIG) benefits from the intrinsic properties of graphene, for example, high conductivity, high electroactivity, and high specific area. In this work the potential of laser‐induced graphene in constructing an enzymatic electrochemical biosensing interface is evaluated. Here, a laminar‐structured laser‐induced graphene material is fabricated by laser engraving with polyimide. After deposition of the electron mediator ferrocene, a conjugated enzyme complex of bovine serum albumin‐glucose oxidase (BSA‐GOx) is modified on the laser‐induced graphene by cross‐linking. The fabricated glucose oxidase/ferrocene/LIG (GOx/Fc/LIG) biosensor achieves high sensitivity of 11.3 µA mM−1 cm−2), wide linear range of 0–11 mM, and low detection of limit of 0.04 µM. The LIG electrodes exhibit high flexibility with bending angle as high as 60° without observed conductivity change. The repeatability and robustness of the developed LIG biosensor in detection of real serum samples empower it with great potential in clinical implementation in the future.

show abstract

MXene‐Based Flexible Sensors: Materials, Preparation, and Applications

Han

Yan

et al. 2023

Adv Materials Technologies

View full text Add to dashboard Cite

The rational design and applications of MXene-based materials have yielded remarkable progress in flexible sensors, including wearable devices, soft robots, and smart medical equipment. The emerging MXene and substrate materials can be precisely engineered to improve the mechanical properties and sensing sensitivity of the sensors, opening up a wider range of application possibilities for MXene-based sensors. Therefore, a systematic and comprehensive review summarizing the progress of MXene-based sensor research based on these backgrounds is necessary. First, we discuss the basic structure of MXene materials and introduce the flexible substrate materials for MXene-based flexible sensors in detail. Then, we also discuss the different preparation methods of MXene-based sensors, describe the classifications, and highlight the applications of MXene-based flexible sensors in various scenarios. Finally, we identify the challenges that need to be overcome to accelerate the development of MXene-based materials in flexible sensing. This review provides a comprehensive and systematic insight into MXene-based flexible sensors and it is expected that this review will contribute to the development of higher performance MXene-based flexible sensors.

show abstract

MXene nanoflakes decorating ZnO tetrapods for enhanced performance of skin-attachable stretchable enzymatic electrochemical glucose sensor

Cited by 105 publications

References 59 publications

Effect of Electrode Modification with Chitosan and Nafion® on the Efficiency of Real-Time Enzyme Glucose Biosensors Based on ZnO Tetrapods

Effect of Electrode Modification with Chitosan and Nafion® on the Efficiency of Real-Time Enzyme Glucose Biosensors Based on ZnO Tetrapods

An Enzymatic Electrochemical Biosensing Interface Developed by The Laser‐Induced Graphene Electrode

MXene‐Based Flexible Sensors: Materials, Preparation, and Applications

Contact Info

Product

Resources

About