MXene/Hydrogel-based bioelectronic nose for the direct evaluation of food spoilage in both liquid and gas-phase environments

Liu, Jing; Nam, Youngju; Choi, Danmin; Choi, Yoonji; Lee, Sang-Eun; Oh, Honggyu; Wang, Guangxian; Lee, Seung Hwan; Liu, Yuan; Hong, Seunghun

doi:10.1016/j.bios.2024.116260

Cited by 4 publications

(3 citation statements)

References 45 publications

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“…35 Similar studies have been conducted on detecting rose scent using human olfactory receptor 1A2 (hOR1A2) MSP NDs 36 or on a hydrogel system to detect volatile gases. 37 Though NDs offer a high degree of compatibility with various techniques, as mentioned in Figure 2, biological atomic force microscopy (bioAFM) offers greater flexibility regarding experimental design and outcomes in interpreting the protein's physical and chemical aspects at physiological conditions.…”

Section: Food-flavor Researchmentioning

confidence: 99%

“…Dose-dependent curves were also generated to determine antagonism-based bitter taste masking . Similar studies have been conducted on detecting rose scent using human olfactory receptor 1A2 (hOR1A2) MSP NDs or on a hydrogel system to detect volatile gases …”

Section: Biomolecular Insights Using Nanodiscs In Food-flavor Researchmentioning

confidence: 99%

“… 35 Similar studies have been conducted on detecting rose scent using human olfactory receptor 1A2 (hOR1A2) MSP NDs 36 or on a hydrogel system to detect volatile gases. 37 …”

Section: Biomolecular Insights Using Nanodiscs In Food-flavor Researchmentioning

confidence: 99%

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Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Karanth,

Benthin,

Wiesenfarth

et al. 2024

J. Agric. Food Chem.

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Chemosensory membrane proteins such as G-protein-coupled receptors (GPCRs) drive flavor perception of food formulations. To achieve this, a detailed understanding of the structure and function of these membrane proteins is needed, which is often limited by the extraction and purification methods involved. The proposed nanodisc methodology helps overcome some of these existing challenges such as protein stability and solubilization along with their reconstitution from a native cell-membrane environment. Being well-established in structural biology procedures, nanodiscs offer this elegant solution by using, e.g., a membrane scaffold protein (MSP) or styrene−maleic acid (SMA) polymer, which interacts directly with the cell membrane during protein reconstitution. Such derived proteins retain their biophysical properties without compromising the membrane architecture. Here, we seek to show that these lipidic systems can be explored for insights with a focus on chemosensory membrane protein morphology and structure, conformational dynamics of protein−ligand interactions, and binding kinetics to answer pending questions in flavor research. Additionally, the compatibility of nanodiscs across varied (labeled or label-free) techniques offers significant leverage, which has been highlighted here.

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Section: Food-flavor Researchmentioning

confidence: 99%

Section: Biomolecular Insights Using Nanodiscs In Food-flavor Researchmentioning

confidence: 99%

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Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Karanth,

Benthin,

Wiesenfarth

et al. 2024

J. Agric. Food Chem.

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Recent advancements in MXenes synthesis, properties, and cutting-edge applications: A comprehensive review

Baghchesaraee,

Ghasali,

Raza

et al. 2024

Journal of Environmental Chemical Engineering

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Room Temperature Sensing Properties of In₂O₃-MXene Composites to NO₂

Zhang,

Li,

et al. 2024

ACS Appl. Electron. Mater.

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With the rapid development of technology, nanocomposite materials are playing an increasingly crucial role in gas-sensing applications. This study focuses on the effective fabrication of In2O3 nanofibers through the electrospinning method. The In2O3 was uniformly dispersed in a preconfigured MXene ethanol solution using ethanol dispersal sample preparation, and the In2O3-MXene composite was successfully produced through ultrasonic drying. The study evaluated the sensitivity of In2O3-MXene composite nanomaterials in detecting NO2 at room temperature. The sensor performance of the MXene composite nanomaterials toward nitrogen dioxide exceeded that of pure In2O3. The sample exhibited a response of up to 3800 for NO2 at 10 ppm, with a detection limit of 50 ppb, showcasing its capability in detecting low NO2 concentrations. Further analysis of the gas-sensitive mechanism revealed that the strong specificity of the composite nanomaterials may stem from the formation of more favorable gas attachment sites on the material surface. The present study provides a greater value for the detection of nitrogen dioxide at low concentrations at room temperature.

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MXene/Hydrogel-based bioelectronic nose for the direct evaluation of food spoilage in both liquid and gas-phase environments

Cited by 4 publications

References 45 publications

Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Recent advancements in MXenes synthesis, properties, and cutting-edge applications: A comprehensive review

Room Temperature Sensing Properties of In₂O₃-MXene Composites to NO₂

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MXene/Hydrogel-based bioelectronic nose for the direct evaluation of food spoilage in both liquid and gas-phase environments

Cited by 4 publications

References 45 publications

Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Nanodisc Technology: Direction toward Physicochemical Characterization of Chemosensory Membrane Proteins in Food Flavor Research

Recent advancements in MXenes synthesis, properties, and cutting-edge applications: A comprehensive review

Room Temperature Sensing Properties of In2O3-MXene Composites to NO2

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Product

Resources

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Room Temperature Sensing Properties of In₂O₃-MXene Composites to NO₂