MWCNTs/Cu(OH)2 nanoparticles/IL nanocomposite modified glassy carbon electrode as a voltammetric sensor for determination of the non-steroidal anti-inflammatory drug diclofenac

Arvand, Majid; Gholizadeh, Tahereh M.; Zanjanchi, Mohammad Ali

doi:10.1016/j.msec.2012.04.066

Cited by 103 publications

(44 citation statements)

References 27 publications

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“…Thisconclusion is in accordance with the mechanism of DS electrochemical reaction as shown in Scheme 1[32,33,35,41]. As shown inFig.…”

supporting

confidence: 89%

“…In view of the prominence of DS in clinical applications, various efforts have been made for the determination of DS, including gas chromatography-mass spectrometry [19,20], liquid chromatography [21][22][23], liquid chromatography-tandem mass spectrometry [24], spectrophotometry [25][26][27][28][29], colorimetry [30], spectrofluorimetry [31], and voltammetry [32][33][34][35][36][37][38][39][40][41][42][43] in biological fluids.…”

Section: Introductionmentioning

confidence: 99%

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Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

Afkhami

Bahiraei

Madrakian

2016

Materials Science and Engineering: C

125

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“…Thisconclusion is in accordance with the mechanism of DS electrochemical reaction as shown in Scheme 1[32,33,35,41]. As shown inFig.…”

supporting

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

Afkhami

Bahiraei

Madrakian

2016

Materials Science and Engineering: C

125

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“…Unfortunately, these methods require frequently a time-consuming initial sample preparation stage due to very low concentrations of DF in water samples.An alternative to the methods described above are electrochemical methods that allow for quick and cheap analysis of real samples. In the research, various types of working electrodes are used, the most popular electrodes are glassy carbon electrodes modified with metal [10], graphene and carbon nanomaterials [1,[11][12][13][14] or organic compounds [15][16][17][18]. In addition, paste electrodes [19] modified with carbon nanomaterials [20-24], silica [25] or organic compounds [26], graphite electrodes [27,28], composite electrodes [27,29], carbon ceramic electrodes [30], boron-doped diamond electrodes [31], and platinum disk electrodes [32,33] are used.…”

mentioning

confidence: 99%

First Electrochemical Sensor (Screen-Printed Carbon Electrode Modified with Carboxyl Functionalized Multiwalled Carbon Nanotubes) for Ultratrace Determination of Diclofenac

et al. 2020

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A simple, sensitive and time-saving differential-pulse adsorptive stripping voltammetric (DPAdSV) procedure using a screen-printed carbon electrode modified with carboxyl functionalized multiwalled carbon nanotubes (SPCE/MWCNTs-COOH) for the determination of diclofenac (DF) is presented. The sensor was characterized using optical profilometry, SEM, and cyclic voltammetry (CV). The use of carboxyl functionalized MWCNTs as a SPCE modifier improved the electron transfer process and the active surface area of sensor. Under optimum conditions, very sensitive results were obtained with a linear range of 0.1-10.0 nmol L −1 and a limit of detection value of 0.028 nmol L −1 . The SPCE/MWCNTs-COOH also exhibited satisfactory repeatability, reproducibility, and selectivity towards potential interferences. Moreover, for the first time, the electrochemical sensor allows determining the real concentrations of DF in environmental water samples without sample pretreatment steps.Keywords: screen-printed carbon electrode modified with carboxyl functionalized multiwalled carbon nanotubes; diclofenac; differential-pulse adsorptive stripping voltammetry; environmental water samples; HPLC with photo-diode array detection Materials 2020, 13, 781 2 of 15 to ground and surface water, causing their pollution. Low water temperatures and short days hinder the process of photolysis and the biodegradation of pharmaceutical preparations, which can cause adverse and unpredictable effects in the ecosystem. The main sources of pollution are factories and production plants, as well as hospitals, health centers, and practically every household. DF is one of the most commonly found ingredients in water, and its concentration is from 3.7 × 10 −11 to 1.4 × 10 −8 mol L −1 [2,3].Although the likelihood of any form of short-term human health risk after DF release into the environment is low, a study links the catastrophic decline of Gyps vulture populations across the Indian subcontinent to DF [4,5]. Generally, NSAIDs such as DF and ibuprofen, for example, have Log Kow values greater than three and may have the capacity to bioaccumulate in the tissues of organisms [6]. DF exhibits acute hepatotoxicity, causes changes in kidneys and gills in rainbow trout (O. mykiss) and exhibits acute toxicity to phytoplankton and zooplankton. Moreover, the possibility of synergetic effects with other pharmaceuticals or chemicals in the aquatic environment increases the environmental risk as well [7].There are many methods in the literature that allow for the determination of DF at various concentration levels. The most popular methods are spectrophotometry (determined DF concentrations: 6.8 × 10 −7 -8.4 × 10 −2 mol L −1 ), spectrofluorimetry (determined DF concentrations: 4.2 × 10 −7 -1.7 × 10 −4 mol L −1 ), calorimetry (determined DF concentrations: 4.6 × 10 −6 -2.7 × 10 −4 mol L −1 ), high-performance thin-layer chromatography (determined DF concentrations: 6.8 × 10 −7 -2.7 × 10 −6 mol L −1 ), and HPLC (determined DF concentrations: 1.7 × 10 −8 -1.4 × 10 −5 mol L −1 )...

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“…From Fig. 30 When the 4-PP-modied GCE is used to sense PCT and DCF simultaneously (as shown in Fig. As shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

4-Phosphatephenyl-modified glassy carbon electrode for real-time and simultaneous electrochemical monitoring of paracetamol and diclofenac release from electrospun nanofibers

Zhou

Wang

et al. 2015

Anal. Methods

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An effective electrochemical platform was set up for the real-time and simultaneous monitoring of the kinetics of drug release from electrospun nanofibers. The method describes the development and utilization of a 4-phosphatephenyl (4-PP)-modified glassy carbon electrode (GCE). The modified electrode was used to monitor paracetamol (PCT) and/or diclofenac (DCF) release from electrospun nanofibers. The drug-loaded nanofibers were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). Using differential pulse voltammetry (DPV), the modified electrode shows good sensitivity and selectivity for the simultaneous determination of PCT (1.87 mM to 170 mΜ) and DCF (0.37s-51.87 mM). The release kinetics study reveals that the drug follows first order kinetics and that the mechanism of drug release was a diffusion-controlled type. No significant drugpolymer interactions were observed in the FTIR studies. The results obtained are promising, which demonstrates that the electrochemical method possesses the capability for the simultaneous detection of multiple molecules in a drug delivery system (DDS).

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MWCNTs/Cu(OH)2 nanoparticles/IL nanocomposite modified glassy carbon electrode as a voltammetric sensor for determination of the non-steroidal anti-inflammatory drug diclofenac

Cited by 103 publications

References 27 publications

Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

Gold nanoparticle/multi-walled carbon nanotube modified glassy carbon electrode as a sensitive voltammetric sensor for the determination of diclofenac sodium

First Electrochemical Sensor (Screen-Printed Carbon Electrode Modified with Carboxyl Functionalized Multiwalled Carbon Nanotubes) for Ultratrace Determination of Diclofenac

4-Phosphatephenyl-modified glassy carbon electrode for real-time and simultaneous electrochemical monitoring of paracetamol and diclofenac release from electrospun nanofibers

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