1999
DOI: 10.1002/(sici)1098-2280(1999)33:3<185::aid-em2>3.0.co;2-t
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Mutation spectrum in Salmonella induced by environmental tobacco smoke

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Cited by 3 publications
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“…It has been reported that G is likely to be misread as a T nucleotide, due to the formation of 8-oxo-dG during NGS sample preparation 22 , 23 ; therefore, it is possible that the sensitivity of G:C > T:A mutation detection was relatively strongly affected by this artificial error. The detection of mutations induced by mutagens that mainly cause G:C > T:A substitution, such as polycyclic aromatic hydrocarbons (PAHs), might be more difficult than detection of mutations caused by other types of mutagens 24 , 25 . Other library preparation and sequencing approaches which consider the sequence of the complementary strand, such as duplex sequences 15 , and circular consensus sequencing 26 , should improve sequence accuracy, although this would be at the expense of sequence efficiency.…”
Section: Discussionmentioning
confidence: 99%
“…It has been reported that G is likely to be misread as a T nucleotide, due to the formation of 8-oxo-dG during NGS sample preparation 22 , 23 ; therefore, it is possible that the sensitivity of G:C > T:A mutation detection was relatively strongly affected by this artificial error. The detection of mutations induced by mutagens that mainly cause G:C > T:A substitution, such as polycyclic aromatic hydrocarbons (PAHs), might be more difficult than detection of mutations caused by other types of mutagens 24 , 25 . Other library preparation and sequencing approaches which consider the sequence of the complementary strand, such as duplex sequences 15 , and circular consensus sequencing 26 , should improve sequence accuracy, although this would be at the expense of sequence efficiency.…”
Section: Discussionmentioning
confidence: 99%