Mutagenicity and Subacute Toxicity of Acanthopanax senticosus Extracts in Rats

Safety and efficacy of a feed additive consisting of a tincture derived from the roots of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (taiga root tincture) for use in dogs, cats and horses (FEFANA asbl)

“…The literature search provided by the applicant also considered the genotoxicity of aqueous and ethanolic extracts obtained from E. senticosus . 25 Although the limited information submitted indicated no concern, the composition of the test items was unknow and major shortcomings in the study design were identified for all the studies provided (Hirosue et al, 1986 ; Park et al, 2006 ; Bespalov et al, 2013 ). Therefore, these studies were not considered relevant for the current assessment.…”